IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Trousdale, M. D.
Right arrow Articles by Miller, C. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Trousdale, M. D.
Right arrow Articles by Miller, C. A.

Investigative Ophthalmology & Visual Science, Vol 20, 230-235, Copyright © 1981 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Assessment of acyclovir on acute ocular infection induced by drug- resistant strains of HSV-1

MD Trousdale, AB Nesburn and CA Miller

Effects of topical acyclovir treatment on rabbit eyes infected with parent McKrae, idoxuridine-resistant, and vidarabine-resistant strains of HSV-1 were studied. Topical acyclovir therapy given four times a day was significantly more effective than idoxuridine and vidarabine at suppressing acute herpetic ocular disease induced by either sensitive or drug-resistant strains of HSV-1. Virus isolation from neural tissues indicated that none of the therapy prevented viral infection of the nervous system.


This article has been cited by other articles:


Home page
 IOVSHome page
K. R. Mott, Y. Osorio, E. Maguen, A. B. Nesburn, A. E. Wittek, S. Cai, S. Chattopadhyay, and H. Ghiasi
Role of Anti-Glycoproteins D (Anti-gD) and K (Anti-gK) IgGs in Pathology of Herpes Stromal Keratitis in Humans
Invest. Ophthalmol. Vis. Sci., May 1, 2007; 48(5): 2185 - 2193.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by the Association for Research in Vision and Ophthalmology