IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jumblatt, M. M.
Right arrow Articles by Neufeld, A. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jumblatt, M. M.
Right arrow Articles by Neufeld, A. H.

Investigative Ophthalmology & Visual Science, Vol 24, 1139-1143, Copyright © 1983 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

Beta-adrenergic and serotonergic responsiveness of rabbit corneal epithelial cells in culture

MM Jumblatt and AH Neufeld

Rabbit corneal epithelial cell cultures were established from Dispase- treated anterior corneas. In culture medium containing cholera toxin, insulin and epidermal growth factor, these cells proliferated in vitro in the absence of any contaminating cells. Following subculture, cells retained epithelial morphology and the ability to synthesize cAMP in response to beta-adrenergic stimulation, but lacked the ability to respond to serotonergic stimulation. Retention of the beta-adrenergic system in culture serves as a functional epithelial cell marker; whereas expression of serotonergic responsiveness may be regulated by developmental or extrapithelial systems that are absent in these cell cultures.


This article has been cited by other articles:


Home page
 IOVSHome page
I. Alarcon, D. J. Evans, and S. M. J. Fleiszig
The Role of Twitching Motility in Pseudomonas aeruginosa Exit from and Translocation of Corneal Epithelial Cells
Invest. Ophthalmol. Vis. Sci., May 1, 2009; 50(5): 2237 - 2244.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
J. Chen, E. Guerriero, K. Lathrop, and N. SundarRaj
Rho/ROCK Signaling in Regulation of Corneal Epithelial Cell Cycle Progression
Invest. Ophthalmol. Vis. Sci., January 1, 2008; 49(1): 175 - 183.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
Y. Liu, L. Gan, D. J. Carlsson, P. Fagerholm, N. Lagali, M. A. Watsky, R. Munger, W. G. Hodge, D. Priest, and M. Griffith
A Simple, Cross-linked Collagen Tissue Substitute for Corneal Implantation
Invest. Ophthalmol. Vis. Sci., May 1, 2006; 47(5): 1869 - 1875.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. Ni, D. J. Evans, S. Hawgood, E. M. Anders, R. A. Sack, and S. M. J. Fleiszig
Surfactant Protein D Is Present in Human Tear Fluid and the Cornea and Inhibits Epithelial Cell Invasion by Pseudomonas aeruginosa
Infect. Immun., April 1, 2005; 73(4): 2147 - 2156.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
E. J. Suuronen, C. R. McLaughlin, P. K. Stys, M. Nakamura, R. Munger, and M. Griffith
Functional Innervation in Tissue Engineered Models for In Vitro Study and Testing Purposes
Toxicol. Sci., December 1, 2004; 82(2): 525 - 533.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. Ueta, T. Nochi, M.-H. Jang, E. J. Park, O. Igarashi, A. Hino, S. Kawasaki, T. Shikina, T. Hiroi, S. Kinoshita, et al.
Intracellularly Expressed TLR2s and TLR4s Contribution to an Immunosilent Environment at the Ocular Mucosal Epithelium
J. Immunol., September 1, 2004; 173(5): 3337 - 3347.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
F. Li, D. Carlsson, C. Lohmann, E. Suuronen, S. Vascotto, K. Kobuch, H. Sheardown, R. Munger, M. Nakamura, and M. Griffith
Cellular and nerve regeneration within a biosynthetic extracellular matrix for corneal transplantation
PNAS, December 23, 2003; 100(26): 15346 - 15351.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
I. Zolfaghar, D. J. Evans, and S. M. J. Fleiszig
Twitching Motility Contributes to the Role of Pili in Corneal Infection Caused by Pseudomonas aeruginosa
Infect. Immun., September 1, 2003; 71(9): 5389 - 5393.
[Abstract] [Full Text] [PDF]

Home page
 J Med MicrobiolHome page
H. ZHU, S. J. THURUTHYIL, and M. D. P. WILLCOX
Determination of quorum-sensing signal molecules and virulence factors of Pseudomonas aeruginosa isolates from contact lens-induced microbial keratitis
J. Med. Microbiol., December 1, 2002; 51(12): 1063 - 1070.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
S. C. Anderson, C. Stone, L. Tkach, and N. SundarRaj
Rho and Rho-Kinase (ROCK) Signaling in Adherens and Gap Junction Assembly in Corneal Epithelium
Invest. Ophthalmol. Vis. Sci., April 1, 2002; 43(4): 978 - 986.
[Abstract] [Full Text] [PDF]

Home page
 Br J OphthalmolHome page
D Meller, R T F Pires, and S C G Tseng
Ex vivo preservation and expansion of human limbal epithelial stem cells on amniotic membrane cultures
Br J Ophthalmol, April 1, 2002; 86(4): 463 - 471.
[Abstract] [Full Text] [PDF]

Home page
 Exp Biol MedHome page
L. Lu, P. S. Reinach, and W. W.-Y. Kao
Corneal Epithelial Wound Healing
Exp Biol Med, July 1, 2001; 226(7): 653 - 664.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
S. C. Anderson and N. SundarRaj
Regulation of a Rho-Associated Kinase Expression during the Corneal Epithelial Cell Cycle
Invest. Ophthalmol. Vis. Sci., April 1, 2001; 42(5): 933 - 940.
[Abstract] [Full Text]

Home page
 Br J OphthalmolHome page
A. Solomon, M. Rosenblatt, D. Monroy, Z. Ji, S. C Pflugfelder, and S. C G Tseng
Suppression of interleukin 1{alpha} and interleukin 1{beta} in human limbal epithelial cells cultured on the amniotic membrane stromal matrix
Br J Ophthalmol, April 1, 2001; 85(4): 444 - 449.
[Abstract] [Full Text]

Home page
 IOVSHome page
T. Bourcier, P. Forgez, V. Borderie, S. Scheer, W. Rostene, and L. Laroche
Regulation of Human Corneal Epithelial Cell Proliferation and Apoptosis by Dexamethasone
Invest. Ophthalmol. Vis. Sci., December 1, 2000; 41(13): 4133 - 4141.
[Abstract] [Full Text]

Home page
 Infect. Immun.Home page
B. A. Cowell, D. Y. Chen, D. W. Frank, A. J. Vallis, and S. M. J. Fleiszig
ExoT of Cytotoxic Pseudomonas aeruginosa Prevents Uptake by Corneal Epithelial Cells
Infect. Immun., January 1, 2000; 68(1): 403 - 406.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
D. J. Evans, D. W. Frank, V. Finck-Barbancon, C. Wu, and S. M. J. Fleiszig
Pseudomonas aeruginosa Invasion and Cytotoxicity Are Independent Events, Both of Which Involve Protein Tyrosine Kinase Activity
Infect. Immun., April 1, 1998; 66(4): 1453 - 1459.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
F Castro-Munozledo
Development of a spontaneous permanent cell line of rabbit corneal epithelial cells that undergoes sequential stages of differentiation in cell culture
J. Cell Sci., January 8, 1994; 107(8): 2343 - 2351.
[Abstract] [PDF]

Home page
 Arch OphthalmolHome page
H. M. Boisjoly, R. Sun, M. Giasson, and A. Beaulieu
Topical Fibronectin and Aprotinin for Keratectomy Wound Healing in Rabbits
Arch Ophthalmol, December 1, 1990; 108(12): 1758 - 1763.
[Abstract] [PDF]

Home page
 Arch OphthalmolHome page
M. I. Roat, G. Sossi, C.-Y. Lo, and R. A. Thoft
Hyperproliferation of Conjunctival Fibroblasts From Patients With Cicatricial Pemphigoid
Arch Ophthalmol, July 1, 1989; 107(7): 1064 - 1067.
[Abstract] [PDF]

Home page
 Arch OphthalmolHome page
K. S. Mallick, A. S. Hajek, and R. K. Parrish II
Fluorouracil (5-FU) and Cytarabine (Ara-C) Inhibition of Corneal Epithelial Cell and Conjunctival Fibroblast Proliferation
Arch Ophthalmol, September 1, 1985; 103(9): 1398 - 1402.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1983 by the Association for Research in Vision and Ophthalmology