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Investigative Ophthalmology & Visual Science, Vol 28, 711-717, Copyright © 1987 by Association for Research in Vision and Ophthalmology

ARTICLES AND REPORTS

A psychophysical technique for measuring cone photopigment bleaching

SA Burns, AE Elsner, LA Lobes Jr and BH Doft

A new, clinically applicable test has been developed to measure the bleaching of the foveal cone photopigments. This noninvasive test is called steady-state color matching. Steady-state color matching is based on the dependence of a color match on the optical density of the cone photopigments. By measuring the color match as a function of retinal illuminance, it is possible to compute the optical density of the cone photopigments at each illuminance. Thus, abnormalities of photopigment bleaching can be detected. This study demonstrates that the technique is readily performed by a clinical population. Patients with central serous retinopathy and retinitis pigmentosa are shown to have low effective optical densities.


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N. P. Davies and A. B. Morland
Color Matching in Diabetes: Optical Density of the Crystalline Lens and Macular Pigments
Invest. Ophthalmol. Vis. Sci., January 1, 2002; 43(1): 281 - 289.
[Abstract] [Full Text] [PDF]


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Copyright © 1987 by the Association for Research in Vision and Ophthalmology