| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 From the Department of Ophthalmology, New York University School of Medicine, and the 2 Department of Psychology, Columbia University, New York, New York.
PURPOSE. To evaluate the nature and extent of retinal dysfunction in the macular and surrounding areas that occurs in patients with diabetes with clinically significant macular edema (CSME).
METHODS. Eleven patients were evaluated before focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to assess the effects of diabetic retinopathy and CSME on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The relationship between local sensitivity changes and local ERG changes was determined.
RESULTS. Local ERG responses were significantly delayed and decreased in amplitude, and timing changes were observed in a larger area of the retina than amplitude changes. Visual field deficits were similarly widespread with marked sensitivity losses occurring in retinal areas with normal ERG amplitudes and in areas that appeared to be free of fundus abnormalities. Despite this similarity and the finding that retinal areas with elevated thresholds have timing delays, timing delays were not good predictors of the degree of threshold elevation.
CONCLUSIONS. The results demonstrate the widespread nature of timing deficits and visual field deficits that are associated with CSME.
This article has been cited by other articles:
|
|
 |
|
  W. Seiple, J. P. Szlyk, J. Paliga, and M. F. Rabb Perifoveal function in patients with north Carolina macular dystrophy: the importance of accounting for fixation locus. Invest. Ophthalmol. Vis. Sci., April 1, 2006; 47(4): 1703 - 1709. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Klemp, B. Sander, P. B. Brockhoff, A. Vaag, H. Lund-Andersen, and M. Larsen The Multifocal ERG in Diabetic Patients without Retinopathy during Euglycemic Clamping Invest. Ophthalmol. Vis. Sci., July 1, 2005; 46(7): 2620 - 2626. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Han, A. J. Adams, M. A. Bearse Jr, and M. E. Schneck Multifocal Electroretinogram and Short-Wavelength Automated Perimetry Measures in Diabetic Eyes With Little or No Retinopathy Arch Ophthalmol, December 1, 2004; 122(12): 1809 - 1815. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Han, M. E. Schneck, M. A. Bearse Jr, S. Barez, C. H. Jacobsen, N. P. Jewell, and A. J. Adams Formulation and Evaluation of a Predictive Model to Identify the Sites of Future Diabetic Retinopathy Invest. Ophthalmol. Vis. Sci., November 1, 2004; 45(11): 4106 - 4112. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Bearse Jr, Y. Han, M. E. Schneck, S. Barez, C. Jacobsen, and A. J. Adams Local Multifocal Oscillatory Potential Abnormalities in Diabetes and Early Diabetic Retinopathy Invest. Ophthalmol. Vis. Sci., September 1, 2004; 45(9): 3259 - 3265. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y Han, M A Bearse Jr, M E Schneck, S Barez, C Jacobsen, and A J Adams Towards optimal filtering of "standard" multifocal electroretinogram (mfERG) recordings: findings in normal and diabetic subjects Br. J. Ophthalmol., April 1, 2004; 88(4): 543 - 550. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Han, M. A. Bearse Jr, M. E. Schneck, S. Barez, C. H. Jacobsen, and A. J. Adams Multifocal Electroretinogram Delays Predict Sites of Subsequent Diabetic Retinopathy Invest. Ophthalmol. Vis. Sci., March 1, 2004; 45(3): 948 - 954. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Bearse Jr, Y. Han, M. E. Schneck, and A. J. Adams Retinal Function in Normal and Diabetic Eyes Mapped with the Slow Flash Multifocal Electroretinogram Invest. Ophthalmol. Vis. Sci., January 1, 2004; 45(1): 296 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-H. Piao, M. Kondo, M. Nakamura, H. Terasaki, and Y. Miyake Multifocal Electroretinograms in X-Linked Retinoschisis Invest. Ophthalmol. Vis. Sci., November 1, 2003; 44(11): 4920 - 4930. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Terasaki, T. Kojima, H. Niwa, C.-H. Piao, S. Ueno, M. Kondo, Y. Ito, and Y. Miyake Changes in Focal Macular Electroretinograms and Foveal Thickness after Vitrectomy for Diabetic Macular Edema Invest. Ophthalmol. Vis. Sci., October 1, 2003; 44(10): 4465 - 4472. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. B. Arden and J. E. Wolf Differential Effects of Light and Alcohol on the Electro-oculographic Responses of Patients with Age-Related Macular Disease Invest. Ophthalmol. Vis. Sci., July 1, 2003; 44(7): 3226 - 3232. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. C. Greenstein, H. Chen, D. C. Hood, K. Holopigian, W. Seiple, and R. E. Carr Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation Invest. Ophthalmol. Vis. Sci., October 1, 2000; 41(11): 3655 - 3664. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
