HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Greenstein, V. C. Articles by Carr, R. E. Search for Related Content PubMed PubMed Citation Articles by Greenstein, V. C. Articles by Carr, R. E.

Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation

¹ From the Department of Ophthalmology, New York University School of Medicine, and the ² Department of Psychology, Columbia University, New York, New York.

PURPOSE. To assess the effects of focal photocoagulation on retinal function in the macular and perimacular areas in patients with diabetes who have clinically significant macular edema.

METHODS. Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to evaluate the effects of treatment on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The posttreatment results were compared with pretreatment results. Changes in local ERG response amplitudes and implicit times were calculated for each patient and presented as difference fields. The changes in local ERG responses were compared with the changes in local field sensitivity.

RESULTS. After treatment, the results of the psychophysical tests suggested little or no change in visual function, but changes in retinal function were observed with the multifocal ERG technique. Local ERG responses showed increases in implicit time and decreases in amplitude, compared with pretreatment values. Timing was affected more than amplitude.

CONCLUSIONS. The results suggest that focal treatment produces changes in retinal function, and these changes are not restricted to the treated macular area.

This article has been cited by other articles:

				K. Klemp, B. Sander, P. B. Brockhoff, A. Vaag, H. Lund-Andersen, and M. Larsen The Multifocal ERG in Diabetic Patients without Retinopathy during Euglycemic Clamping Invest. Ophthalmol. Vis. Sci., July 1, 2005; 46(7): 2620 - 2626. [Abstract] [Full Text] [PDF]

				Y. Han, A. J. Adams, M. A. Bearse Jr, and M. E. Schneck Multifocal Electroretinogram and Short-Wavelength Automated Perimetry Measures in Diabetic Eyes With Little or No Retinopathy Arch Ophthalmol, December 1, 2004; 122(12): 1809 - 1815. [Abstract] [Full Text] [PDF]

				Y. Han, M. E. Schneck, M. A. Bearse Jr, S. Barez, C. H. Jacobsen, N. P. Jewell, and A. J. Adams Formulation and Evaluation of a Predictive Model to Identify the Sites of Future Diabetic Retinopathy Invest. Ophthalmol. Vis. Sci., November 1, 2004; 45(11): 4106 - 4112. [Abstract] [Full Text] [PDF]

				Y Han, M A Bearse Jr, M E Schneck, S Barez, C Jacobsen, and A J Adams Towards optimal filtering of "standard" multifocal electroretinogram (mfERG) recordings: findings in normal and diabetic subjects Br J Ophthalmol, April 1, 2004; 88(4): 543 - 550. [Abstract] [Full Text] [PDF]

				Y. Han, M. A. Bearse Jr, M. E. Schneck, S. Barez, C. H. Jacobsen, and A. J. Adams Multifocal Electroretinogram Delays Predict Sites of Subsequent Diabetic Retinopathy Invest. Ophthalmol. Vis. Sci., March 1, 2004; 45(3): 948 - 954. [Abstract] [Full Text] [PDF]

				M. A. Bearse Jr, Y. Han, M. E. Schneck, and A. J. Adams Retinal Function in Normal and Diabetic Eyes Mapped with the Slow Flash Multifocal Electroretinogram Invest. Ophthalmol. Vis. Sci., January 1, 2004; 45(1): 296 - 304. [Abstract] [Full Text] [PDF]

				H. Terasaki, T. Kojima, H. Niwa, C.-H. Piao, S. Ueno, M. Kondo, Y. Ito, and Y. Miyake Changes in Focal Macular Electroretinograms and Foveal Thickness after Vitrectomy for Diabetic Macular Edema Invest. Ophthalmol. Vis. Sci., October 1, 2003; 44(10): 4465 - 4472. [Abstract] [Full Text] [PDF]

				B. Falsini, F. Focosi, F. Molle, C. Manganelli, G. Iarossi, A. Fadda, G. Dorin, and M. A. Mainster Monitoring Retinal Function during Transpupillary Thermotherapy for Occult Choroidal Neovascularization in Age-Related Macular Degeneration Invest. Ophthalmol. Vis. Sci., May 1, 2003; 44(5): 2133 - 2140. [Abstract] [Full Text] [PDF]

				V. C. Greenstein, K. Holopigian, D. C. Hood, W. Seiple, and R. E. Carr The Nature and Extent of Retinal Dysfunction Associated with Diabetic Macular Edema Invest. Ophthalmol. Vis. Sci., October 1, 2000; 41(11): 3643 - 3654. [Abstract] [Full Text]