IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wesendahl, T.
Right arrow Articles by Frenz, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wesendahl, T.
Right arrow Articles by Frenz, M.
(Investigative Ophthalmology and Visual Science. 2000;41:505-512.)
© 2000 by The Association for Research in Vision and Ophthalmology, Inc.

Erbium:YAG Laser Ablation of Retinal Tissue under Perfluorodecaline: Determination of Laser–Tissue Interaction in Pig Eyes

Thomas Wesendahl1, Peter Janknecht1, Bea Ott2 and Martin Frenz2

1 From the Department of Ophthalmology, University of Freiburg, Germany; and 2 the Institute of Applied Physics, University of Berne, Switzerland.

PURPOSE. To evaluate the effect of Er:YAG laser on pig retina using a perfluorodecaline/retina interphase with the goal of precisely determining the extent of retinal tissue ablation.

METHODS. Free running ({tau} = 250 µsec) Er:YAG laser pulses were transmitted through a zirconium fluoride (ZrF4) fiber guarded by quartz rod (d = 1000 µm). Laser pulses were applied to the retinal surface of enucleated pig eyes. Eyes were mounted in a specially designed rotating sample holder. The fiber probe was elevated 1.0 ± 0.3 mm above the retinal surface with perfluorodecaline serving as transmitting medium. The laser energy was applied in a circular pattern with a radius of 3.0 mm. Radiant exposures were set to 1, 3, 5, and 10 J/cm2.

RESULTS. Tissue ablation linearly increased with radiant exposure from 3.2 ± 3.7 µm at 1 J/cm2 up to 40.9 ± 12.9 µm at 10 J/cm2. Thermal tissue changes extended 70 ± 10 µm vertically into the retina and 25 ± 5 µm horizontally. Distortion of outer photoreceptor segments was noticed when the retina was exposed to radiant exposures of 3 J/cm2 or higher.

CONCLUSIONS. The Er:YAG laser in combination with perfluorodecaline produced precise ablation of the pig retina, which suggests the feasibility of this technique for safe ablation of epiretinal membranes.




This article has been cited by other articles:


Home page
 IOVSHome page
D. V. Palanker, J. M. Miller, M. F. Marmor, S. R. Sanislo, P. Huie, and M. S. Blumenkranz
Pulsed Electron Avalanche Knife (PEAK) for Intraocular Surgery
Invest. Ophthalmol. Vis. Sci., October 1, 2001; 42(11): 2673 - 2678.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2000 by the Association for Research in Vision and Ophthalmology