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(Investigative Ophthalmology and Visual Science. 2006;47:1895-1901.)
© 2006 by The Association for Research in Vision and Ophthalmology, Inc.
DOI:  10.1167/iovs.05-0802
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Strip Meniscometry: A New and Simple Method of Tear Meniscus Evaluation

Murat Dogru,1,2 Katsushi Ishida,3 Yukihiro Matsumoto,1 Eiki Goto,2 Misaki Ishioka,4 Takashi Kojima,5 Tateki Goto,6 Megumi Saeki,2 and Kazuo Tsubota2

1From the Department of Ophthalmology, Tokyo Dental College, Ichikawa, Japan; 2Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan; 3Maruishi Kasei Research, Tokyo, Japan; 4Ryogoku Eye Clinic, Tokyo, Japan; 5Eye Clinic, Nagoya Social Insurance Chukyo Hospital, Nagoya, Japan; and the 6Statistics Group, Santen Pharmaceuticals, Osaka, Japan.

PURPOSE. To investigate the applicability and efficacy of a new and simple method of quantification of the volume of tear meniscus, termed "strip meniscometry," in the diagnosis of the dry eye syndromes in a prospective controlled study.

METHODS. One hundred eyes of 50 patients with dry eye (19 males; 31 females) aged between 18 and 76 years (mean, 54.3 years), as well as 80 eyes of 40 normal subjects aged from 15 to 70 years (mean, 50.8 years; 12 males, 28 females) were recruited in this study. The patients and the control subjects underwent strip meniscometry for 5 seconds, tear film lipid layer interferometry, tear film break-up time measurement, and ocular surface vital staining with fluorescein and rose bengal dyes and the Schirmer-1 test.

RESULTS. Strip meniscometry scores correlated with tear quantity and stability, ocular surface staining scores, and lipid layer interferometry grades and improved after 2 weeks of punctal plug occlusion.

CONCLUSIONS. Strip meniscometry is a swift, noninvasive, promising new method that is expected to find application in the diagnosis and evaluation of the outcome of treatment of dry eye syndromes.






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