IOVS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Originally published In Press as doi:10.1167/iovs.08-2745 on May 14, 2009
 (Investigative Ophthalmology and Visual Science. 2009;50:4110-4113.)
© 2009 by The Association for Research in Vision and Ophthalmology, Inc.
doi:10.1167/iovs.08-2745
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
iovs.08-2745v1
50/9/4110    most recent
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Google Scholar
Right arrow Articles by Tan, G. S.
Right arrow Articles by Aung, T.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tan, G. S.
Right arrow Articles by Aung, T.

Is Routine Pupil Dilation Safe among Asian Patients with Diabetes?

Gavin S. Tan,1,2 Ching-Yee Wong,1,2 Tien Yin Wong,1,3,4,5 Chitra V. Govindasamy,1 Edmund Y. Wong,1 Ian Y. Yeo,1 and Tin Aung1,3,4

1From the Singapore National Eye Centre, Singapore; the 3Singapore Eye Research Institute, Singapore; the 4Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; and the 5Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia.

PURPOSE. To investigate the risk of acute angle closure (AAC), changes in intraocular pressure (IOP), and factors associated with these outcomes after routine pupil dilation in a cohort of Asian subjects with diabetes mellitus.

METHODS. The study was a prospective observational case series of 1910 consecutive Asian subjects newly referred for assessment of diabetic retinopathy at a tertiary clinic. All subjects underwent routine pupil dilation unless there was a prior history of angle-closure glaucoma. Noncontact air-puff tonometry was used to assess IOP, which was measured by the same observer before and 1 hour after pupil dilation. Subjects were assessed for signs and symptoms of AAC before leaving the clinic, and their charts were also subsequently reviewed for revisits with AAC.

RESULTS. Of the 1910 subjects who participated, none developed AAC. Sixty-nine subjects (3.6%, 95% CI: 2.8%–4.5%) showed an increase in IOP of ≥5 mm Hg in the either eye, 37 subjects (1.9%, 95% CI: 1.4%–2.6%) had a postdilation IOP >25 mm Hg in either eye, and only 10 subjects (0.52%, 95% CI: 0.25%–0.96%) had an increase in IOP ≥5 mm Hg and had a postdilation IOP >25 mm Hg in either eye. The level of predilation IOP and a known history of glaucoma were significant risk factors for a postdilation IOP ≥25 mm Hg.

CONCLUSIONS. In this cohort of Asian persons with diabetes, the risk of AAC was insignificant after routine dilation of pupils for fundus examination. These data substantiate the safety of routine dilation of pupils in Asian patients with diabetes.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2009 by the Association for Research in Vision and Ophthalmology