Regulation of Corneal Fibroblast Morphology and Collagen Reorganization by Extracellular Matrix Mechanical Properties
Invest. Ophthalmol. Vis. Sci. Karamichos et al.
48: 5030
Movies
Files in this Data Supplement:
Movie 1
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4 MB (.mov)
Color overlay of f-actin (green) and collagen fibils (red) shown over a range of projection angles for a cell cultured for 24 hours within the A-zone of a CO construct. The cell has a bipolar morphology. Note that there is compaction and alignment of collagen fibrils parallel to the ends of the pseudopodia.
Movie 2
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5 MB (.mov)
Color overlay of f-actin (green) and collagen fibils (red) shown over a range of projection angles for a cell cultured for 24 hours within the A-zone of a UN construct. The cell has a bipolar morphology. No consistent pattern of cell-induced collagen compaction and alignment is observed.
Movie 3
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5.75 MB (.mov)
Color overlay of f-actin (green) and collagen fibils (red) shown over a range of projection angles for two adjacent cells cultured for 24 hours within the A-zone of a CO construct. A band of highly compacted and aligned collagen between the ends the two cells is observed.
