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Article |
1 Department of Ophthalmology, University of Dresden, Fetscherstr. 74, Dresden, 01307, Germany
2 Department of Ophthalmology, University of Dresden, Dresden, Germany
3 Institute of Medical Statistics and Biometry, University of Dresden, Dresden, Germany
* To whom correspondence should be addressed. E-mail: boehm{at}uniklinikum-dresden.de.
| Abstract |
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Purpose: The aim of the study was to examine the effect of central corneal thickness (CCT), corneal curvature, astigmatism, axial length (AL), and age on measurements with the Pascal Dynamic Contour Tonometer (DCT). Methods: In a prospective clinical trial 75 eyes of 75 patients undergoing phacoemulsification were examined. Before phacoemulsification the anterior chamber was cannulated at the temporal corneal limbus. In a closed system the IOP was directly set to 15, 20 and 35 mmHg by manometric water column. IOP measurements taken by DCT were compared to intracameral measurements with a precision reference pressure sensor. Results: Measurements from 60 patients were suitable for statistical analysis. At the IOP level of 15 mmHg mean differences between IOP measured by DCT and intracameral IOP were -0.02±1.32 mmHg, -0.2±1.44 mmHg at the IOP level of 20 mmHg and -0.84±1.90 mmHg at the level of 35 mmHg, respectively. The concordance coefficient according to Lin was 0.9763 showing good agreement between DCT and intracameral IOP. There was a statistically significant correlation between the difference of IOP measured by DCT minus intracameral IOP and CCT with P=0.0291 and R2=0.00012. All other parameters had no statistically significant effect on the difference of DCT and intracameral IOP (corneal curvature (P=0.6094, R2=0.00367), age (P=0.9198, R2=0.000003), astigmatism (P=0.1564, R2=0.08497), and axial length (P=0.9484, R2=0.00008)). Conclusions: Measurements with the DCT showed a good concordance with the intracameral IOP. Central corneal thickness showed a statistically significant but clinically irrelevant effect on measurements with the DCT.
Key Words: glaucoma, tonometry, intraocular pressure
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