Lecture:

Scott M. Whitcup

The Double-Edged Ocular Immune Response: The Cogan Lecture
2000 41: 3243-3248. [Full Text] [PDF]  

Anatomy and Pathology:

Michele Crisp, Kerry Jo Starkey, Carol Lane, Jack Ham, and Marian Ludgate

Adipogenesis in Thyroid Eye Disease
2000 41: 3249-3255. [Abstract] [Full Text] [PDF]  

Michael D. Abràmoff, Ad P. G. Van Gils, Gerard H. Jansen, and Maarten P. Mourits

MRI Dynamic Color Mapping: A New Quantitative Technique for Imaging Soft Tissue Motion in the Orbit
2000 41: 3256-3260. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Tomohiko Usui, Shiro Amano, Tetsuro Oshika, Kaori Suzuki, Kazunori Miyata, Makoto Araie, Paraskevi Heldin, and Hidetoshi Yamashita

Expression Regulation of Hyaluronan Synthase in Corneal Endothelial Cells
2000 41: 3261-3267. [Abstract] [Full Text] [PDF]  

Akira Kobayashi, Tomomi Higashide, Duco Hamasaki, Shinya Kubota, Hitoshi Sakuma, Weijun An, Takuro Fujimaki, Margaret J. McLaren, Richard G. Weleber, and George Inana

HRG4 (UNC119) Mutation Found in Cone–Rod Dystrophy Causes Retinal Degeneration in a Transgenic Model
2000 41: 3268-3277. [Abstract] [Full Text] [PDF]  

J. Bronwyn Bateman, David D. Geyer, Pamela Flodman, Meriam Johannes, James Sikela, Nicole Walter, Ana Teresa Moreira, Kevin Clancy, and M. Anne Spence

A New ßA1-Crystallin Splice Junction Mutation in Autosomal Dominant Cataract
2000 41: 3278-3285. [Abstract] [Full Text] [PDF]  

Alan E. A. Ridgway, Saeed Akhtar, Francis L. Munier, Daniel F. Schorderet, Helen Stewart, Ramat Perveen, Richard E. Bonshek, Monica T. P. Odenthal, Michael Dixon, Rafael Barraquer, Remberto Escoto, and Graeme C. M. Black

Ultrastructural and Molecular Analysis of Bowman’s Layer Corneal Dystrophies: An Epithelial Origin?
2000 41: 3286-3292. [Abstract] [Full Text] [PDF]  

Camus Kar Man Choy, Iris Frances Forster Benzie, and Pauline Cho

Ascorbic Acid Concentration and Total Antioxidant Activity of Human Tear Fluid Measured Using the FRASC Assay
2000 41: 3293-3298. [Abstract] [Full Text] [PDF]  

Anne Vaughan–Thomas, Sophie J. Gilbert, and Victor C. Duance

Elevated Levels of Proteolytic Enzymes in the Aging Human Vitreous
2000 41: 3299-3304. [Abstract] [Full Text] [PDF]  

Stefania Bortoluzzi, Fabio d’Alessi, and Gian Antonio Danieli

A Novel Resource for the Study of Genes Expressed in the Adult Human Retina
2000 41: 3305-3308. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Roger C. W. Wolfs, Petra H. Borger, Raan S. Ramrattan, Caroline C. W. Klaver, Caroline A. A. Hulsman, Albert Hofman, Johannes R. Vingerling, Roger A. Hitchings, and Paulus T. V. M. de Jong

Changing Views on Open-Angle Glaucoma: Definitions and Prevalences—The Rotterdam Study
2000 41: 3309-3321. [Abstract] [Full Text] [PDF]  

Tos T. J. M. Berendschot, R. Alexandra Goldbohm, Wilhelmina A. A. Klöpping, Jan van de Kraats, Jeannette van Norel, and Dirk van Norren

Influence of Lutein Supplementation on Macular Pigment, Assessed with Two Objective Techniques
2000 41: 3322-3326. [Abstract] [Full Text] [PDF]  

Gary S. Rubin, Beatriz Muñoz, Karen Bandeen–Roche, and Sheila K. West

Monocular versus Binocular Visual Acuity as Measures of Vision Impairment and Predictors of Visual Disability
2000 41: 3327-3334. [Abstract] [Full Text] [PDF]  

Cornea:

Louise Mulroy, June Kim, Irene Wu, Philip Scharper, Samir A. Melki, Dimitri T. Azar, Robert W. Redmond, and Irene E. Kochevar

Photochemical Keratodesmos for Repair of Lamellar Corneal Incisions
2000 41: 3335-3340. [Abstract] [Full Text] [PDF]  

Sushma Hegde and Jerry Y. Niederkorn

The Role of Cytotoxic T Lymphocytes in Corneal Allograft Rejection
2000 41: 3341-3347. [Abstract] [Full Text] [PDF]  

P. Ewen King-Smith, Barbara A. Fink, Nick Fogt, Kelly K. Nichols, Richard M. Hill, and Graeme S. Wilson

The Thickness of the Human Precorneal Tear Film: Evidence from Reflection Spectra
2000 41: 3348-3359. [Abstract] [Full Text] [PDF]  

Svein Estil, Earl J. Primo, and Graeme Wilson

Apoptosis in Shed Human Corneal Cells
2000 41: 3360-3364. [Abstract] [Full Text] [PDF]  

Shukti Chakravarti, W. Matthew Petroll, John R. Hassell, James V. Jester, Jonathan H. Lass, Jennifer Paul, and David E. Birk

Corneal Opacity in Lumican-Null Mice: Defects in Collagen Fibril Structure and Packing in the Posterior Stroma
2000 41: 3365-3373. [Abstract] [Full Text] [PDF]  

Chia Lin Chu, Wende R. Reenstra, Daniel L. Orlow, and Kathy Kay Hartford Svoboda

Erk and PI-3 Kinase Are Necessary for Collagen Binding and Actin Reorganization in Corneal Epithelia
2000 41: 3374-3382. [Abstract] [Full Text] [PDF]  

Tomohiro Ikeda, Hidemi Ishii, Toshiyuki Higuchi, Keiko Sato, Yasuhito Hayashi, Kozo Ikeda, and Yoshifumi Hirabayashi

Localization of Thrombomodulin in the Anterior Segment of the Human Eye
2000 41: 3383-3390. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Neal A. Rubinstein and Joseph Foon Yoong Hoh

The Distribution of Myosin Heavy Chain Isoforms among Rat Extraocular Muscle Fiber Types
2000 41: 3391-3398. [Abstract] [Full Text] [PDF]  

Nilza Minguini, Keila M. Monteiro de Carvalho, Patrícia M. S. Akaishi, and Iara M. S. De Luca

Histologic Effect of Mitomycin C on Strabismus Surgery in the Rabbit
2000 41: 3399-3401. [Abstract] [Full Text] [PDF]  

Stephen P. Christiansen, Amy Sandnas, Robert Prill, Richard J. Youle, and Linda K. McLoon

Acute Effects of the Skeletal Muscle-Specific Immunotoxin Ricin-mAb 35 on Extraocular Muscles of Rabbits
2000 41: 3402-3409. [Abstract] [Full Text] [PDF]  

Eileen E. Birch, William H. Swanson, and Yi-Zhong Wang

Infant Hyperacuity for Radial Deformation
2000 41: 3410-3414. [Abstract] [Full Text] [PDF]  

Glaucoma:

Lijun Jia, William O. Cepurna, Elaine C. Johnson, and John C. Morrison

Effect of General Anesthetics on IOP in Rats with Experimental Aqueous Outflow Obstruction
2000 41: 3415-3419. [Abstract] [Full Text] [PDF]  

Ruth E. Swiderski, Jean L. Ross, John H. Fingert, Abbot F. Clark, Wallace L. M. Alward, Edwin M. Stone, and Val C. Sheffield

Localization of MYOC Transcripts in Human Eye and Optic Nerve by In Situ Hybridization
2000 41: 3420-3428. [Abstract] [Full Text] [PDF]  

Natalie Hutchings, John M. Wild, Michael K. Hussey, John G. Flanagan, and Graham E. Trope

The Long-Term Fluctuation of the Visual Field in Stable Glaucoma
2000 41: 3429-3436. [Abstract] [Full Text] [PDF]  

Junping Li, Brenda J. Tripathi, and Ramesh C. Tripathi

Modulation of Pre-mRNA Splicing and Protein Production of Fibronectin by TGF-ß2 in Porcine Trabecular Cells
2000 41: 3437-3443. [Abstract] [Full Text] [PDF]  

Atsushi Kawasaki, Yasumasa Otori, and Colin J. Barnstable

Müller Cell Protection of Rat Retinal Ganglion Cells from Glutamate and Nitric Oxide Neurotoxicity
2000 41: 3444-3450. [Abstract] [Full Text] [PDF]  

Thom W. Mittag, John Danias, Geralyn Pohorenec, Hong–Mei Yuan, Evren Burakgazi, Ruth Chalmers–Redman, Steven M. Podos, and William G. Tatton

Retinal Damage after 3 to 4 Months of Elevated Intraocular Pressure in a Rat Glaucoma Model
2000 41: 3451-3459. [Abstract] [Full Text] [PDF]  

Harry A. Quigley, Stuart J. McKinnon, Donald J. Zack, Mary Ellen Pease, Lisa A. Kerrigan–Baumrind, Danielle F. Kerrigan, and Rebecca S. Mitchell

Retrograde Axonal Transport of BDNF in Retinal Ganglion Cells Is Blocked by Acute IOP Elevation in Rats
2000 41: 3460-3466. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Hartmut Wenkel and J. Wayne Streilein

Evidence that Retinal Pigment Epithelium Functions as an Immune-Privileged Tissue
2000 41: 3467-3473. [Abstract] [Full Text] [PDF]  

Narciss Okhravi, Peter Adamson, Nora Carroll, Anthony Dunlop, Melville M. Matheson, Hamish M. A. Towler, and Susan Lightman

PCR-Based Evidence of Bacterial Involvement in Eyes with Suspected Intraocular Infection
2000 41: 3474-3479. [Abstract] [Full Text] [PDF]  

Marc D. de Smet and Molly Dayan

Prospective Determination of T-Cell Responses to S-Antigen in Behçet’s Disease Patients and Controls
2000 41: 3480-3484. [Abstract] [Full Text] [PDF]  

François Willermain, Laure Caspers–Velu, Nathalie Baudson, Christine Dubois, Malika Hamdane, Fabienne Willems, Thierry Velu, and Catherine Bruyns

Role and Expression of CD40 on Human Retinal Pigment Epithelial Cells
2000 41: 3485-3491. [Abstract] [Full Text] [PDF]  

Jeong-Hyeon Sohn, Henry J. Kaplan, Hye-Jung Suk, Puran S. Bora, and Nalini S. Bora

Chronic Low Level Complement Activation within the Eye Is Controlled by Intraocular Complement Regulatory Proteins
2000 41: 3492-3502. [Abstract] [Full Text] [PDF]  

Lens:

Lilley Leong, A. Sue Menko, and Gerald B. Grunwald

Differential Expression of N- and B-Cadherin during Lens Development
2000 41: 3503-3510. [Abstract] [Full Text] [PDF]  

Eran Pras, Moshe Frydman, Etgar Levy–Nissenbaum, Tengiz Bakhan, Judith Raz, Ehud I. Assia, Boleslaw Goldman, and Elon Pras

A Nonsense Mutation (W9X) in CRYAA Causes Autosomal Recessive Cataract in an Inbred Jewish Persian Family
2000 41: 3511-3515. [Abstract] [Full Text] [PDF]  

Sandra Priolo, Jacob G. Sivak, Jer R. Kuszak, and Elizabeth L. Irving

Effects of Experimentally Induced Ametropia on the Morphology and Optical Quality of the Avian Crystalline Lens
2000 41: 3516-3522. [Abstract] [Full Text] [PDF]  

Max B. Kelz, Jer R. Kuszak, Yinqing Yang, Wanchao Ma, Cathy Steffen, Kirsten Al-Ghoul, Ya-Jun Zhang, Jingshan Chen, Eric J. Nestler, and Abraham Spector

FosB-Induced Cataract
2000 41: 3523-3538. [Abstract] [Full Text] [PDF]  

Marcelo N. Ayala, Ralph Michael, and Per G. Söderberg

Influence of Exposure Time for UV Radiation–Induced Cataract
2000 41: 3539-3543. [Abstract] [Full Text] [PDF]  

Angela M. Hales, Coral G. Chamberlain, and John W. McAvoy

Susceptibility to TGFß2-Induced Cataract Increases with Aging in the Rat
2000 41: 3544-3551. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Elínborg Gudmundsdóttir, Einar Stefánsson, Gyda Bjarnadóttir, Jóhanna F. Sigurjónsdóttir, Gudrún Gudmundsdóttir, Mar Masson, and Thorsteinn Loftsson

Methazolamide 1% in Cyclodextrin Solution Lowers IOP in Human Ocular Hypertension
2000 41: 3552-3554. [Abstract] [Full Text] [PDF]  

Christophe Delaey, Koen Boussery, and Johan Van de Voorde

A Retinal-Derived Relaxing Factor Mediates the Hypoxic Vasodilation of Retinal Arteries
2000 41: 3555-3560. [Abstract] [Full Text] [PDF]  

Retina:

Alistair J. Barber, David A. Antonetti, and Thomas W. Gardner

Altered Expression of Retinal Occludin and Glial Fibrillary Acidic Protein in Experimental Diabetes
2000 41: 3561-3568. [Abstract] [Full Text] [PDF]  

Glenn J. Jaffe, Chang Hao Yang, Hong Guo, John P. Denny, Cristiana Lima, and Paul Ashton

Safety and Pharmacokinetics of an Intraocular Fluocinolone Acetonide Sustained Delivery Device
2000 41: 3569-3575. [Abstract] [Full Text] [PDF]  

Ray F. Gariano, Anjali K. Nath, Donald J. D’Amico, Thomas Lee, and M. Rocio Sierra–Honigmann

Elevation of Vitreous Leptin in Diabetic Retinopathy and Retinal Detachment
2000 41: 3576-3581. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Judit Baffi, Gordon Byrnes, Chi–Chao Chan, and Karl G. Csaky

Choroidal Neovascularization in the Rat Induced by Adenovirus Mediated Expression of Vascular Endothelial Growth Factor
2000 41: 3582-3589. [Abstract] [Full Text] [PDF]  

Lisa L. Cunningham and Federico Gonzalez–Fernandez

Coordination between Production and Turnover of Interphotoreceptor Retinoid-Binding Protein in Zebrafish
2000 41: 3590-3599. [Abstract] [Full Text] [PDF]  

Tatiana Gründer, Konrad Kohler, and Elke Guenther

Distribution and Developmental Regulation of AMPA Receptor Subunit Proteins in Rat Retina
2000 41: 3600-3606. [Abstract] [Full Text] [PDF]  

Hiroto Shibuki, Naomichi Katai, Junji Yodoi, Koji Uchida, and Nagahisa Yoshimura

Lipid Peroxidation and Peroxynitrite in Retinal Ischemia–Reperfusion Injury
2000 41: 3607-3614. [Abstract] [Full Text] [PDF]  

Christian K. Vorwerk, Rita Naskar, Frank Schuettauf, Kristine Quinto, David Zurakowski, Gordon Gochenauer, Michael B. Robinson, Scott A. Mackler, and Evan B. Dreyer

Depression of Retinal Glutamate Transporter Function Leads to Elevated Intravitreal Glutamate Levels and Ganglion Cell Death
2000 41: 3615-3621. [Abstract] [Full Text] [PDF]  

Dana Lau, Laura H. McGee, Shangzhen Zhou, Katherine G. Rendahl, William C. Manning, Jaime A. Escobedo, and John G. Flannery

Retinal Degeneration Is Slowed in Transgenic Rats by AAV-Mediated Delivery of FGF-2
2000 41: 3622-3633. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Jennifer Kang Derwent and Robert A. Linsenmeier

Effects of Hypoxemia on the a- and b-Waves of the Electroretinogram in the Cat Retina
2000 41: 3634-3642. [Abstract] [Full Text] [PDF]  

Vivienne C. Greenstein, Karen Holopigian, Donald C. Hood, William Seiple, and Ronald E. Carr

The Nature and Extent of Retinal Dysfunction Associated with Diabetic Macular Edema
2000 41: 3643-3654. [Abstract] [Full Text] [PDF]  

Vivienne C. Greenstein, Haifan Chen, Donald C. Hood, Karen Holopigian, William Seiple, and Ronald E. Carr

Retinal Function in Diabetic Macular Edema after Focal Laser Photocoagulation
2000 41: 3655-3664. [Abstract] [Full Text] [PDF]  

Erratum:

Erratum
2000 41: 3260. [Abstract] [Full Text] [PDF]  

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