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Cover: Double immunofluorescence (S100 protein red, CD34 green) of histologic section of choroidal melanoma: two small vessels, lined entirely by CD34 (green) are identified, surrounded by tumor cells that express only S100 protein (red) and tumor cells that express both S100 protein and CD34 (yellow). The labeling of melanoma cells by an endothelial cell marker may contribute to calculations of microvascular density. Therefore, microvascular density may not be an exclusive measure of tumor vascularity. See article by Chen et al. on page 2533 of this issue.
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