New Developments:

Algis J. Vingrys and Andrew J. Zele

Robust Indices of Clinical Data: Meaningless Means
2005 46: 4353-4357. [Full Text] [PDF]  

Anatomy and Pathology:

Katia Cortese, Francesca Giordano, Enrico M. Surace, Consuelo Venturi, Andrea Ballabio, Carlo Tacchetti, and Valeria Marigo

The Ocular Albinism Type 1 (OA1) Gene Controls Melanosome Maturation and Size
2005 46: 4358-4364. [Abstract] [Full Text] [PDF]  

Yong Li, Jian Wang, Syed M. Abbas Rizvi, Martine J. Jager, Robert M. Conway, Francis A. Billson, Barry J. Allen, and Michele C. Madigan

In Vitro Targeting of NG2 Antigen by ²¹³Bi-9.2.27 -Immunoconjugate Induces Cytotoxicity in Human Uveal Melanoma Cells
2005 46: 4365-4371. [Abstract] [Full Text] [PDF]  

Mario A. Economou, Charlotta All-Ericsson, Vladimir Bykov, Leonard Girnita, Armando Bartolazzi, Olle Larsson, and Stefan Seregard

Receptors for the Liver Synthesized Growth Factors IGF-1 and HGF/SF in Uveal Melanoma: Intercorrelation and Prognostic Implications
2005 46: 4372-4375. [Abstract] [Full Text] [PDF]  

Paula L. Blanco, Jean Claude A. Marshall, Emilia Antecka, Sonia A. Callejo, Joao P. Souza Filho, Vinicius Saraiva, and Miguel N. Burnier, Jr

Characterization of Ocular and Metastatic Uveal Melanoma in an Animal Model
2005 46: 4376-4382. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Juan Amaral, Robert N. Fariss, Maria M. Campos, W. Gerald Robison, Jr, Hyuncheol Kim, Robert Lutz, and S. Patricia Becerra

Transscleral-RPE Permeability of PEDF and Ovalbumin Proteins: Implications for Subconjunctival Protein Delivery
2005 46: 4383-4392. [Abstract] [Full Text] [PDF] Supplementary Material  

Roxana A. Radu, Yun Han, Tam V. Bui, Steven Nusinowitz, Dean Bok, Jay Lichter, Ken Widder, Gabriel H. Travis, and Nathan L. Mata

Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases
2005 46: 4393-4401. [Abstract] [Full Text] [PDF]  

Janos Hargitai, Jana Zernant, Gabor M. Somfai, Rita Vamos, Agnes Farkas, Gyorgy Salacz, and Rando Allikmets

Correlation of Clinical and Genetic Findings in Hungarian Patients with Stargardt Disease
2005 46: 4402-4408. [Abstract] [Full Text] [PDF] Supplementary Figures  

Hadas Mechoulam and Eric A. Pierce

Expression and Activation of STAT3 in Ischemia-Induced Retinopathy
2005 46: 4409-4416. [Abstract] [Full Text] [PDF]  

V. John Hindson, John T. Gallagher, Willi Halfter, and Paul N. Bishop

Opticin Binds to Heparan and Chondroitin Sulfate Proteoglycans
2005 46: 4417-4423. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Elvis Ojaimi, Ian G. Morgan, Dana Robaei, Kathryn A. Rose, Wayne Smith, Elena Rochtchina, and Paul Mitchell

Effect of Stature and Other Anthropometric Parameters on Eye Size and Refraction in a Population-Based Study of Australian Children
2005 46: 4424-4429. [Abstract] [Full Text] [PDF]  

Shiao Hui Melissa Liew, Clare E. Gilbert, Tim D. Spector, John Mellerio, John Marshall, Fredericus J. van Kuijk, Stephen Beatty, Fred Fitzke, and Christopher J. Hammond

Heritability of Macular Pigment: A Twin Study
2005 46: 4430-4436. [Abstract] [Full Text] [PDF]  

Gerald McGwin, Jr, Aiyuan Xie, Andrew Mays, Wade Joiner, Dawn K. DeCarlo, Tyler Andrew Hall, and Cynthia Owsley

Visual Field Defects and the Risk of Motor Vehicle Collisions among Patients with Glaucoma
2005 46: 4437-4441. [Abstract] [Full Text] [PDF]  

Sannapaneni Krishnaiah, Taraprasad Das, Praveen K. Nirmalan, Rishita Nutheti, Bindiganavale R. Shamanna, Gullapalli N. Rao, and Ravi Thomas

Risk Factors for Age-Related Macular Degeneration: Findings from the Andhra Pradesh Eye Disease Study in South India
2005 46: 4442-4449. [Abstract] [Full Text] [PDF]  

Chrisandra Shufelt, Samantha Fraser-Bell, Mei Ying-Lai, Mina Torres, Rohit Varma the Los Angeles Latino Eye Study Group

Refractive Error, Ocular Biometry, and Lens Opalescence in an Adult Population: The Los Angeles Latino Eye Study
2005 46: 4450-4460. [Abstract] [Full Text] [PDF]  

Lingam Vijaya, Ronnie George, Pradeep G. Paul, Mani Baskaran, Hemamalini Arvind, Prema Raju, S. Ve Ramesh, Govindasamy Kumaramanickavel, and Catherine McCarty

Prevalence of Open-Angle Glaucoma in a Rural South Indian Population
2005 46: 4461-4467. [Abstract] [Full Text] [PDF]  

Cornea:

Robert Montés-Micó, Jorge L. Alió, and W. Neil Charman

Postblink Changes in the Ocular Modulation Transfer Function Measured by a Double-Pass Method
2005 46: 4468-4473. [Abstract] [Full Text] [PDF]  

Pasquale Aragona, Claudio Bucolo, Rosaria Spinella, Sebastiano Giuffrida, and Giuseppe Ferreri

Systemic Omega-6 Essential Fatty Acid Treatment and PGE₁ Tear Content in Sjögren’s Syndrome Patients
2005 46: 4474-4479. [Abstract] [Full Text] [PDF]  

Rhian Gwilliam, Petra Liskova, Martin Filipec, Stanislav Kmoch, Katerina Jirsova, Elizabeth J. Huckle, Catherine L. Stables, Shomi S. Bhattacharya, Alison J. Hardcastle, Panos Deloukas, and Neil D. Ebenezer

Posterior Polymorphous Corneal Dystrophy in Czech Families Maps to Chromosome 20 and Excludes the VSX1 Gene
2005 46: 4480-4484. [Abstract] [Full Text] [PDF]  

Dipika V. Patel and Charles N. J. McGhee

Mapping of the Normal Human Corneal Sub-Basal Nerve Plexus by In Vivo Laser Scanning Confocal Microscopy
2005 46: 4485-4488. [Abstract] [Full Text] [PDF]  

Satoru Yamagami, Seiichi Yokoo, Tomohiko Usui, Hiroko Yamagami, Shiro Amano, and Nobuyuki Ebihara

Distinct Populations of Dendritic Cells in the Normal Human Donor Corneal Epithelium
2005 46: 4489-4494. [Abstract] [Full Text] [PDF]  

MinHee K. Ko and EunDuck P. Kay

Regulatory Role of FGF-2 on Type I Collagen Expression during Endothelial Mesenchymal Transformation
2005 46: 4495-4503. [Abstract] [Full Text] [PDF]  

John D. Gottsch, Cheng Zhang, Olof H. Sundin, W. Robert Bell, Walter J. Stark, and W. Richard Green

Fuchs Corneal Dystrophy: Aberrant Collagen Distribution in an L450W Mutant of the COL8A2 Gene
2005 46: 4504-4511. [Abstract] [Full Text] [PDF]  

Naoko Okada, Kazumi Fukagawa, Yoji Takano, Murat Dogru, Kazuo Tsubota, Hiroshi Fujishima, Kenji Matsumoto, Toshiharu Nakajima, and Hirohisa Saito

The Implications of the Upregulation of ICAM-1/VCAM-1 Expression of Corneal Fibroblasts on the Pathogenesis of Allergic Keratopathy
2005 46: 4512-4518. [Abstract] [Full Text] [PDF]  

Yoko Ogawa, Hiroaki Kodama, Kaori Kameyama, Kazuto Yamazaki, Hidekata Yasuoka, Shinichiro Okamoto, Hidetoshi Inoko, Yutaka Kawakami, and Masataka Kuwana

Donor Fibroblast Chimerism in the Pathogenic Fibrotic Lesion of Human Chronic Graft-Versus-Host Disease
2005 46: 4519-4527. [Abstract] [Full Text] [PDF]  

Edgar M. Espana, Tetsuya Kawakita, Mario A. Di Pascuale, Wei Li, Lung-Kun Yeh, Jean-Marie Parel, Chia-Yang Liu, and Scheffer C. G. Tseng

The Heterogeneous Murine Corneal Stromal Cell Populations In Vitro
2005 46: 4528-4535. [Abstract] [Full Text] [PDF] Supplementary Video  

Lu Chen, Claus Cursiefen, Stefano Barabino, Qiang Zhang, and M. Reza Dana

Novel Expression and Characterization of Lymphatic Vessel Endothelial Hyaluronate Receptor 1 (LYVE-1) by Conjunctival Cells
2005 46: 4536-4540. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Francisco H. Andrade, Colleen A. McMullen, and Rolando E. Rumbaut

Mitochondria Are Fast Ca²⁺ Sinks in Rat Extraocular Muscles: A Novel Regulatory Influence on Contractile Function and Metabolism
2005 46: 4541-4547. [Abstract] [Full Text] [PDF]  

Kadriye Zeynep Konakci, Johannes Streicher, Wolfram Hoetzenecker, Ines Haberl, Michael Josef Franz Blumer, Grazyna Wieczorek, Josef Gottfried Meingassner, Szabolcs Levente Paal, Daniel Holzinger, Julius-Robert Lukas, and Roland Blumer

Palisade Endings in Extraocular Muscles of the Monkey are Immunoreactive for Choline Acetyltransferase and Vesicular Acetylcholine Transporter
2005 46: 4548-4554. [Abstract] [Full Text] [PDF]  

Hang Yin, John S. Stahl, Francisco H. Andrade, Colleen A. McMullen, Sarah Webb-Wood, Nancy J. Newman, Valerie Biousse, Douglas C. Wallace, and Machelle T. Pardue

Eliminating the Ant1 Isoform Produces a Mouse with CPEO Pathology but Normal Ocular Motility
2005 46: 4555-4562. [Abstract] [Full Text] [PDF]  

Sean I. Chen, Anthony M. Norcia, Mark W. Pettet, and Arvind Chandna

Measurement of Position Acuity in Strabismus and Amblyopia: Specificity of the Vernier VEP Paradigm
2005 46: 4563-4570. [Abstract] [Full Text] [PDF]  

Glaucoma:

Jonathan G. Crowston, James D. Lindsey, Christy A. Morris, Larry Wheeler, Felipe A. Medeiros, and Robert N. Weinreb

Effect of Bimatoprost on Intraocular Pressure in Prostaglandin FP Receptor Knockout Mice
2005 46: 4571-4577. [Abstract] [Full Text] [PDF]  

Jose M. Martinez-de-la-Casa, Julian Garcia-Feijoo, Alfredo Castillo, and Julian Garcia-Sanchez

Reproducibility and Clinical Evaluation of Rebound Tonometry
2005 46: 4578-4580. [Abstract] [Full Text] [PDF]  

Mitra Sehi, John G. Flanagan, Leilei Zeng, Richard J. Cook, and Graham E. Trope

Anterior Optic Nerve Capillary Blood Flow Response to Diurnal Variation of Mean Ocular Perfusion Pressure in Early Untreated Primary Open-Angle Glaucoma
2005 46: 4581-4587. [Abstract] [Full Text] [PDF]  

Xiang-Run Huang and Robert W. Knighton

Microtubules Contribute to the Birefringence of the Retinal Nerve Fiber Layer
2005 46: 4588-4593. [Abstract] [Full Text] [PDF]  

Jean-Marc Guenoun, Christophe Baudouin, Patrice Rat, Aude Pauly, Jean-Michel Warnet, and Françoise Brignole-Baudouin

In Vitro Comparison of Cytoprotective and Antioxidative Effects of Latanoprost, Travoprost, and Bimatoprost on Conjunctiva-Derived Epithelial Cells
2005 46: 4594-4599. [Abstract] [Full Text] [PDF]  

Paul H. Artes, Marcelo T. Nicolela, Raymond P. LeBlanc, and Balwantray C. Chauhan

Visual Field Progression in Glaucoma: Total Versus Pattern Deviation Analyses
2005 46: 4600-4606. [Abstract] [Full Text] [PDF]  

Xinyu Zhang, Abbot F. Clark, and Thomas Yorio

Regulation of Glucocorticoid Responsiveness in Glaucomatous Trabecular Meshwork Cells by Glucocorticoid Receptor-ß
2005 46: 4607-4616. [Abstract] [Full Text] [PDF]  

Wan-Heng Wang, J. Cameron Millar, Iok-Hou Pang, Martin B. Wax, and Abbot F. Clark

Noninvasive Measurement of Rodent Intraocular Pressure with a Rebound Tonometer
2005 46: 4617-4621. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Naoko Asano-Kato, Kazumi Fukagawa, Naoko Okada, Murat Dogru, Kazuo Tsubota, and Hiroshi Fujishima

Tryptase Increases Proliferative Activity of Human Conjunctival Fibroblasts through Protease-Activated Receptor-2
2005 46: 4622-4626. [Abstract] [Full Text] [PDF]  

Susan G. Elner, Howard R. Petty, Victor M. Elner, Ayako Yoshida, Zong-Mei Bian, Dongli Yang, and Andrei L. Kindzelskii

TLR4 Mediates Human Retinal Pigment Epithelial Endotoxin Binding and Cytokine Expression
2005 46: 4627-4633. [Abstract] [Full Text] [PDF]  

Lens:

Lucinda J. G. Robertson, James D. Morton, Masazumi Yamaguchi, Roy Bickerstaffe, Thomas R. Shearer, and Mitsuyoshi Azuma

Calpain May Contribute to Hereditary Cataract Formation in Sheep
2005 46: 4634-4640. [Abstract] [Full Text] [PDF]  

M. Francis Simpanya, Rafat R. Ansari, Kwang I. Suh, Victor R. Leverenz, and Frank J. Giblin

Aggregation of Lens Crystallins in an In Vivo Hyperbaric Oxygen Guinea Pig Model of Nuclear Cataract: Dynamic Light-Scattering and HPLC Analysis
2005 46: 4641-4651. [Abstract] [Full Text] [PDF]  

Qi Yan, Nikole Perdue, David Blake, and E. Helene Sage

Absence of SPARC in Murine Lens Epithelium Leads to Increased Deposition of Laminin-1 in Lens Capsule
2005 46: 4652-4660. [Abstract] [Full Text] [PDF]  

William Pendergrass, Philip Penn, Daniel Possin, and Norman Wolf

Accumulation of DNA, Nuclear and Mitochondrial Debris, and ROS at Sites of Age-Related Cortical Cataract in Mice
2005 46: 4661-4670. [Abstract] [Full Text] [PDF]  

Jochen Graw, Jana Löster, Oliver Puk, Doris Münster, Nicole Haubst, Dian Soewarto, Helmut Fuchs, Birgit Meyer, Peter Nürnberg, Walter Pretsch, Paul Selby, Jack Favor, Eckhard Wolf, and Martin Hrabé de Angelis

Three Novel Pax6 Alleles in the Mouse Leading to the Same Small-Eye Phenotype Caused by Different Consequences at Target Promoters
2005 46: 4671-4683. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Takatoshi Kobayashi, Hidehiro Oku, Masayuki Fukuhara, Shota Kojima, Asako Komori, Masaki Ichikawa, Kozo Katsumura, Masato Kobayashi, Tetsuya Sugiyama, and Tsunehiko Ikeda

Endothelin-1 Enhances Glutamate-Induced Retinal Cell Death, Possibly through ET_A Receptors
2005 46: 4684-4690. [Abstract] [Full Text] [PDF]  

B’Ann T. Gabelt, Mehmet Okka, Tom R. Dean, and Paul L. Kaufman

Aqueous Humor Dynamics in Monkeys after Topical R-DOI
2005 46: 4691-4696. [Abstract] [Full Text] [PDF]  

Mayssa Attar, Kah-Hiing John Ling, Diane D.-S. Tang-Liu, Nouri Neamati, and Vincent H. L. Lee

Cytochrome P450 3A Expression and Activity in the Rabbit Lacrimal Gland: Glucocorticoid Modulation and the Impact on Androgen Metabolism
2005 46: 4697-4706. [Abstract] [Full Text] [PDF]  

Retina:

Michel Paques, Pascale Massin, José A. Sahel, Alain Gaudric, Jean-François Bergmann, Suzanne Azancot, Bernard I. Lévy, and Eric Vicaut

Circadian Fluctuations of Macular Edema in Patients with Morning Vision Blurring: Correlation with Arterial Pressure and Effect of Light Deprivation
2005 46: 4707-4711. [Abstract] [Full Text] [PDF]  

Stuart J. McGimpsey, Jayne V. Woodside, Louise Bamford, Sarah E. C. M. Gilchrist, Ryan Graydon, Gareth C. McKeeman, Ian S. Young, Anne E. Hughes, Chris C. Patterson, Dermot O’Reilly, David McGibbon, and Usha Chakravarthy

Retinal Vein Occlusion, Homocysteine, and Methylene Tetrahydrofolate Reductase Genotype
2005 46: 4712-4716. [Abstract] [Full Text] [PDF]  

Michael Tittl, Noemi Maar, Elzbieta Polska, Günther Weigert, Michael Stur, and Leopold Schmetterer

Choroidal Hemodynamic Changes during Isometric Exercise in Patients with Inactive Central Serous Chorioretinopathy
2005 46: 4717-4721. [Abstract] [Full Text] [PDF]  

Beatrix Feigl, Brian Brown, Jan Lovie-Kitchin, and Peter Swann

Adaptation Responses in Early Age-Related Maculopathy
2005 46: 4722-4727. [Abstract] [Full Text] [PDF]  

Dao-Yi Yu, Stephen J. Cringle, and Er-Ning Su

Intraretinal Oxygen Distribution in the Monkey Retina and the Response to Systemic Hyperoxia
2005 46: 4728-4733. [Abstract] [Full Text] [PDF]  

Rony Gelman, M. Elena Martinez-Perez, Deborah K. Vanderveen, Anne Moskowitz, and Anne B. Fulton

Diagnosis of Plus Disease in Retinopathy of Prematurity Using Retinal Image multiScale Analysis
2005 46: 4734-4738. [Abstract] [Full Text] [PDF]  

Artur V. Cideciyan, Malgorzata Swider, Tomas S. Aleman, Alexander Sumaroka, Sharon B. Schwartz, Marisa I. Roman, Ann H. Milam, Jean Bennett, Edwin M. Stone, and Samuel G. Jacobson

ABCA4-Associated Retinal Degenerations Spare Structure and Function of the Human Parapapillary Retina
2005 46: 4739-4746. [Abstract] [Full Text] [PDF]  

Shin-ichi Manabe, Zezong Gu, and Stuart A. Lipton

Activation of Matrix Metalloproteinase-9 via Neuronal Nitric Oxide Synthase Contributes to NMDA-Induced Retinal Ganglion Cell Death
2005 46: 4747-4753. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Quansheng Xi, Gayle J. T. Pauer, Alan D. Marmorstein, John W. Crabb, and Stephanie A. Hagstrom

Tubby-like Protein 1 (TULP1) Interacts with F-actin in Photoreceptor Cells
2005 46: 4754-4761. [Abstract] [Full Text] [PDF]  

Ann C. Morris, Eric H. Schroeter, Joseph Bilotta, Rachel O. L. Wong, and James M. Fadool

Cone Survival Despite Rod Degeneration in XOPS-mCFP Transgenic Zebrafish
2005 46: 4762-4771. [Abstract] [Full Text] [PDF]  

Shikun He, Yi Ding, Jiehao Zhou, Valery Krasnoperov, Sergey Zozulya, S. Ram Kumar, Stephen J. Ryan, Parkash S. Gill, and David R. Hinton

Soluble EphB4 Regulates Choroidal Endothelial Cell Function and Inhibits Laser-Induced Choroidal Neovascularization
2005 46: 4772-4779. [Abstract] [Full Text] [PDF]  

Min Heui Yoo, Hyae-Jung Hyun, Jae-Young Koh, and Young Hee Yoon

Riluzole Inhibits VEGF-Induced Endothelial Cell Proliferation In Vitro and Hyperoxia-Induced Abnormal Vessel Formation In Vivo
2005 46: 4780-4787. [Abstract] [Full Text] [PDF]  

Patrick T. Johnson, Meghan N. Brown, Bryce C. Pulliam, Don H. Anderson, and Lincoln V. Johnson

Synaptic Pathology, Altered Gene Expression, and Degeneration in Photoreceptors Impacted by Drusen
2005 46: 4788-4795. [Abstract] [Full Text] [PDF]  

Pamela Maher and Anne Hanneken

Flavonoids Protect Retinal Ganglion Cells from Oxidative Stress–Induced Death
2005 46: 4796-4803. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Heather A. Hancock, Clyde Guidry, Russell W. Read, Edgar L. Ready, and Timothy W. Kraft

Acute Aminoglycoside Retinal Toxicity In Vivo and In Vitro
2005 46: 4804-4808. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Dora Fix Ventura, Peter Quiros, Valerio Carelli, Solange R. Salomão, Mirella Gualtieri, André G. F. Oliveira, Marcelo F. Costa, Adriana Berezovsky, Federico Sadun, Anna Maria de Negri, and Alfredo A. Sadun

Chromatic and Luminance Contrast Sensitivities in Asymptomatic Carriers from a Large Brazilian Pedigree of 11778 Leber Hereditary Optic Neuropathy
2005 46: 4809-4814. [Abstract] [Full Text] [PDF]  

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