Research Opportunities:

Michael P. Fautsch, Douglas H. Johnson, and the Second ARVO/Pfizer Research Institute Working Group

Aqueous Humor Outflow: What Do We Know? Where Will It Lead Us?
2006 47: 4181-4187. [Full Text] [PDF]  

Anatomy and Pathology:

Daniel Kjellgren, Per Stål, Lars Larsson, Dieter Fürst, and Fatima Pedrosa-Domellöf

Uncoordinated Expression of Myosin Heavy Chains and Myosin-Binding Protein C Isoforms in Human Extraocular Muscles
2006 47: 4188-4193. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Paul N. Baird, F. M. Amirul Islam, Andrea J. Richardson, Melinda Cain, Nicola Hunt, and Robyn Guymer

Analysis of the Y402H Variant of the Complement Factor H Gene in Age-Related Macular Degeneration
2006 47: 4194-4198. [Abstract] [Full Text] [PDF]  

Karine Zaniolo, Marie-Ève Gingras, Marie Audette, and Sylvain L. Guérin

Expression of the Gene Encoding Poly(ADP-ribose) Polymerase-1 Is Modulated by Fibronectin during Corneal Wound Healing
2006 47: 4199-4210. [Abstract] [Full Text] [PDF]  

Khaled K. Abu-Amero and Thomas M. Bosley

Mitochondrial Abnormalities in Patients with LHON-like Optic Neuropathies
2006 47: 4211-4220. [Abstract] [Full Text] [PDF] Supplementary Tables  

Nelly Buron, Olivier Micheau, Séverine Cathelin, Pierre-Olivier Lafontaine, Catherine Creuzot-Garcher, and Eric Solary

Differential Mechanisms of Conjunctival Cell Death Induction by Ultraviolet Irradiation and Benzalkonium Chloride
2006 47: 4221-4230. [Abstract] [Full Text] [PDF]  

Peter McGannon, Yasumasa Miyazaki, Pankaj C. Gupta, Elias I. Traboulsi, and Clemencia Colmenares

Ocular Abnormalities in Mice Lacking the Ski Proto-oncogene
2006 47: 4231-4237. [Abstract] [Full Text] [PDF]  

Pamela M. Martin, Jaya P. Gnana-Prakasam, Penny Roon, Robert G. Smith, Sylvia B. Smith, and Vadivel Ganapathy

Expression and Polarized Localization of the Hemochromatosis Gene Product HFE in Retinal Pigment Epithelium
2006 47: 4238-4244. [Abstract] [Full Text] [PDF]  

Yi Pan, Srivamsi Nekkalapudi, Lisa E. Kelly, and Heithem M. El-Hodiri

The Rx-like Homeobox Gene (Rx-L) Is Necessary for Normal Photoreceptor Development
2006 47: 4245-4253. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Alicja R. Rudnicka, Shahrul Mt-Isa, Christopher G. Owen, Derek G. Cook, and Deborah Ashby

Variations in Primary Open-Angle Glaucoma Prevalence by Age, Gender, and Race: A Bayesian Meta-Analysis
2006 47: 4254-4261. [Abstract] [Full Text] [PDF]  

Melanie Chak, Angela Wade, Jugnoo Sangeeta Rahi on behalf of the British Congenital Cataract Interest Group

Long-Term Visual Acuity and Its Predictors after Surgery for Congenital Cataract: Findings of the British Congenital Cataract Study
2006 47: 4262-4269. [Abstract] [Full Text] [PDF]  

Jean-François Korobelnik, Nicholas Moore, Patrick Blin, Chandrabhan Dharmani, and Gilles Berdeaux

Estimating the Yearly Number of Eyes with Treatable Neovascular Age-Related Macular Degeneration Using a Direct Standardization Method and a Markov Model
2006 47: 4270-4276. [Abstract] [Full Text] [PDF]  

Richard A. Stone, Lorri B. Wilson, Gui-shuang Ying, Chengcheng Liu, Jonathan S. Criss, Joshua Orlow, Jon M. Lindstrom, and Graham E. Quinn

Associations between Childhood Refraction and Parental Smoking
2006 47: 4277-4287. [Abstract] [Full Text] [PDF]  

Cornea:

Russell L. McCally, Patrick J. Connolly, Walter J. Stark, Sandeep Jain, and Dimitri T. Azar

Identical Excimer Laser PTK Treatments in Rabbits Result in Two Distinct Haze Responses
2006 47: 4288-4294. [Abstract] [Full Text] [PDF]  

Louis Tong, Zhuo Chen, Cintia S. De Paiva, Roger Beuerman, De-Quan Li, and Stephen C. Pflugfelder

Transglutaminase Participates in UVB-Induced Cell Death Pathways in Human Corneal Epithelial Cells
2006 47: 4295-4301. [Abstract] [Full Text] [PDF]  

Lisa Keay, Katie Edwards, Thomas Naduvilath, Kevin Forde, and Fiona Stapleton

Factors Affecting the Morbidity of Contact Lens–Related Microbial Keratitis: A Population Study
2006 47: 4302-4308. [Abstract] [Full Text] [PDF]  

Alan Tomlinson, Santosh Khanal, Kanna Ramaesh, Charles Diaper, and Angus McFadyen

Tear Film Osmolarity: Determination of a Referent for Dry Eye Diagnosis
2006 47: 4309-4315. [Abstract] [Full Text] [PDF]  

Andrew Hopkinson, Richard S. McIntosh, Patrick J. Tighe, David K. James, and Harminder S. Dua

Amniotic Membrane for Ocular Surface Reconstruction: Donor Variations and the Effect of Handling on TGF-ß Content
2006 47: 4316-4322. [Abstract] [Full Text] [PDF]  

Kazuhiro Kimura, Koji Kawamoto, Shinichiro Teranishi, and Teruo Nishida

Role of Rac1 in Fibronectin-Induced Adhesion and Motility of Human Corneal Epithelial Cells
2006 47: 4323-4329. [Abstract] [Full Text] [PDF]  

Kikuko Enomoto, Tatsuya Mimura, Deshea L. Harris, and Nancy C. Joyce

Age Differences in Cyclin-Dependent Kinase Inhibitor Expression and Rb Hyperphosphorylation in Human Corneal Endothelial Cells
2006 47: 4330-4340. [Abstract] [Full Text] [PDF]  

Xinping C. Zhao, Richard W. Yee, Evan Norcom, Heather Burgess, Andrei S. Avanesov, Jim P. Barrish, and Jarema Malicki

The Zebrafish Cornea: Structure and Development
2006 47: 4341-4348. [Abstract] [Full Text] [PDF]  

Jianhua Wang, James Aquavella, Jayachandra Palakuru, Suk Chung, and Changyong Feng

Relationships between Central Tear Film Thickness and Tear Menisci of the Upper and Lower Eyelids
2006 47: 4349-4355. [Abstract] [Full Text] [PDF]  

Bupe R. Mwaikambo, Florian Sennlaub, Huy Ong, Sylvain Chemtob, and Pierre Hardy

Activation of CD36 Inhibits and Induces Regression of Inflammatory Corneal Neovascularization
2006 47: 4356-4364. [Abstract] [Full Text] [PDF]  

Marc H. Levin and A. S. Verkman

Aquaporin-3-Dependent Cell Migration and Proliferation during Corneal Re-epithelialization
2006 47: 4365-4372. [Abstract] [Full Text] [PDF]  

Nilanjana Deb-Joardar, Gilles Thuret, Georges-André Racine, David Pons, Gerald Brun, Olivier Parriaux, Michel Peoc’h, Sophie Acquart, and Philippe Gain

Standard Microlithographic Mosaics to Assess Endothelial Cell Counting Methods by Light Microscopy in Eye Banks Using Organ Culture
2006 47: 4373-4377. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

John Y. Chen, Donald C. Hood, Jeffrey G. Odel, and Myles M. Behrens

The Effects of Retinal Abnormalities on the Multifocal Visual Evoked Potential
2006 47: 4378-4385. [Abstract] [Full Text] [PDF]  

Kourosh Sabri, Christopher M. Knapp, John R. Thompson, and Irene Gottlob

The VF-14 and Psychological Impact of Amblyopia and Strabismus
2006 47: 4386-4392. [Abstract] [Full Text] [PDF]  

Sjoukje E. Loudon, Maria Fronius, Caspar W. N. Looman, Musarat Awan, Brigitte Simonsz, Paul J. van der Maas, and Huibert J. Simonsz

Predictors and a Remedy for Noncompliance with Amblyopia Therapy in Children Measured with the Occlusion Dose Monitor
2006 47: 4393-4400. [Abstract] [Full Text] [PDF]  

Ronit Ram-Tsur, Miriam Faust, Avi Caspi, Carlos R. Gordon, and Ari Z. Zivotofsky

Evidence for Ocular Motor Deficits in Developmental Dyslexia: Application of the Double-Step Paradigm
2006 47: 4401-4409. [Abstract] [Full Text] [PDF]  

Glaucoma:

Jose M. Martinez-de-la-Casa, Julian Garcia-Feijoo, Ana Fernandez-Vidal, Carmen Mendez-Hernandez, and Julian Garcia-Sanchez

Ocular Response Analyzer versus Goldmann Applanation Tonometry for Intraocular Pressure Measurements
2006 47: 4410-4414. [Abstract] [Full Text] [PDF]  

Andrew J. Patterson, David F. Garway-Heath, and David P. Crabb

Improving the Repeatability of Topographic Height Measurements in Confocal Scanning Laser Imaging Using Maximum-Likelihood Deconvolution
2006 47: 4415-4421. [Abstract] [Full Text] [PDF]  

Teruyo Kida, John H. K. Liu, and Robert N. Weinreb

Effect of 24-Hour Corneal Biomechanical Changes on Intraocular Pressure Measurement
2006 47: 4422-4426. [Abstract] [Full Text] [PDF]  

Hiroshi Sakai, Bum-Chan Park, Xiang Shen, and Beatrice Y. J. T. Yue

Transduction of TAT Fusion Proteins into the Human and Bovine Trabecular Meshwork
2006 47: 4427-4434. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Sherry T. Hikita, Barbara P. Vistica, Heather R. Jones, Jennifer R. Keswani, Morgan M. Watson, Vivian R. Ericson, George S. Ayoub, Igal Gery, and Dennis O. Clegg

Osteopontin Is Proinflammatory in Experimental Autoimmune Uveitis
2006 47: 4435-4443. [Abstract] [Full Text] [PDF]  

Qianli Meng, Peizeng Yang, Bing Li, Hongyan Zhou, Xiangkun Huang, Lianxiang Zhu, Yalin Ren, and Aize Kijlstra

CD4⁺PD-1⁺ T Cells Acting as Regulatory Cells during the Induction of Anterior Chamber-Associated Immune Deviation
2006 47: 4444-4452. [Abstract] [Full Text] [PDF]  

Mahesh B. K. Bandara, Hua Zhu, Padmaja R. Sankaridurg, and Mark D. P. Willcox

Salicylic Acid Reduces the Production of Several Potential Virulence Factors of Pseudomonas aeruginosa Associated with Microbial Keratitis
2006 47: 4453-4460. [Abstract] [Full Text] [PDF]  

Michelle C. Callegan, Billy D. Novosad, Raul Ramirez, Emilia Ghelardi, and Sonia Senesi

Role of Swarming Migration in the Pathogenesis of Bacillus Endophthalmitis
2006 47: 4461-4467. [Abstract] [Full Text] [PDF]  

Joveeta Joseph, Savitri Sharma, Somasheila I. Murthy, Pravin V. Krishna, Prashant Garg, Rishita Nutheti, John Kenneth, and Dorairajan Balasubramanian

Microsporidial Keratitis in India: 16S rRNA Gene-Based PCR Assay for Diagnosis and Species Identification of Microsporidia in Clinical Samples
2006 47: 4468-4473. [Abstract] [Full Text] [PDF]  

Lens:

Adam M. DeRosa, Rickie Mui, Miduturu Srinivas, and Thomas W. White

Functional Characterization of a Naturally Occurring Cx50 Truncation
2006 47: 4474-4481. [Abstract] [Full Text] [PDF]  

Niranjan Awasthi and B. J. Wagner

Suppression of Human Lens Epithelial Cell Proliferation by Proteasome Inhibition, a Potential Defense against Posterior Capsular Opacification
2006 47: 4482-4489. [Abstract] [Full Text] [PDF]  

Gregory F. Weber and A. Sue Menko

Phosphatidylinositol 3-Kinase Is Necessary for Lens Fiber Cell Differentiation and Survival
2006 47: 4490-4499. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Aránzazu Mediero, Assumpta Peral, and Jesús Pintor

Dual Roles of Diadenosine Polyphosphates in Corneal Epithelial Cell Migration
2006 47: 4500-4506. [Abstract] [Full Text] [PDF]  

Li Li, Dan-Ning Hu, Huiquan Zhao, Steven A. McCormick, James J. Nordlund, and Raymond E. Boissy

Uveal Melanocytes Do Not Respond To or Express Receptors for -Melanocyte-Stimulating Hormone
2006 47: 4507-4512. [Abstract] [Full Text] [PDF]  

Narayan P. S. Cheruvu and Uday B. Kompella

Bovine and Porcine Transscleral Solute Transport: Influence of Lipophilicity and the Choroid–Bruch’s Layer
2006 47: 4513-4522. [Abstract] [Full Text] [PDF]  

Retina:

Ronja Bahadori, Oliver Rinner, Helia Berrit Schonthaler, Oliver Biehlmaier, Yuri V. Makhankov, Prashanth Rao, Pudur Jagadeeswaran, and Stephan C. F. Neuhauss

The Zebrafish fade out Mutant: A Novel Genetic Model for Hermansky–Pudlak Syndrome
2006 47: 4523-4531. [Abstract] [Full Text] [PDF]  

Ricardo A. Pontes de Carvalho, Melissa L. Krausse, A. Linn Murphree, Edward E. Schmitt, Peter A. Campochiaro, and Irene H. Maumenee

Delivery from Episcleral Exoplants
2006 47: 4532-4539. [Abstract] [Full Text] [PDF]  

Akiko Maeda, Tadao Maeda, and Krzysztof Palczewski

Improvement in Rod and Cone Function in Mouse Model of Fundus albipunctatus after Pharmacologic Treatment with 9-cis-Retinal
2006 47: 4540-4546. [Abstract] [Full Text] [PDF]  

Kimimasa Muranaka, Yasuo Yanagi, Yasuhiro Tamaki, Tomohiko Usui, Naoto Kubota, Aya Iriyama, Yasuo Terauchi, Takashi Kadowaki, and Makoto Araie

Effects of Peroxisome Proliferator-Activated Receptor and Its Ligand on Blood–Retinal Barrier in a Streptozotocin-Induced Diabetic Model
2006 47: 4547-4552. [Abstract] [Full Text] [PDF]  

Almut Bindewald-Wittich, Meng Han, Steffen Schmitz-Valckenberg, Sarah R. Snyder, Günter Giese, Josef F. Bille, and Frank G. Holz

Two-Photon–Excited Fluorescence Imaging of Human RPE Cells with a Femtosecond Ti:Sapphire Laser
2006 47: 4553-4557. [Abstract] [Full Text] [PDF]  

Vidyullatha Vasireddy, Monica M. Jablonski, Md Nawajes A. Mandal, Dorit Raz-Prag, Xiaofei F. Wang, Lesli Nizol, Alessandro Iannaccone, David C. Musch, Ronald A. Bush, Norman Salem, Jr, Paul A. Sieving, and Radha Ayyagari

Elovl4 5-bp–Deletion Knock-in Mice Develop Progressive Photoreceptor Degeneration
2006 47: 4558-4568. [Abstract] [Full Text] [PDF] Supplementary Figure  

Rogério A. Costa, Rodrigo Jorge, Daniela Calucci, José A. Cardillo, Luiz A. S. Melo, Jr, and Ingrid U. Scott

Intravitreal Bevacizumab for Choroidal Neovascularization Caused by AMD (IBeNA Study): Results of a Phase 1 Dose-Escalation Study
2006 47: 4569-4578. [Abstract] [Full Text] [PDF]  

Lori S. Sullivan, Sara J. Bowne, C. Robyn Seaman, Susan H. Blanton, Richard A. Lewis, John R. Heckenlively, David G. Birch, Dianna Hughbanks-Wheaton, and Stephen P. Daiger

Genomic Rearrangements of the PRPF31 Gene Account for 2.5% of Autosomal Dominant Retinitis Pigmentosa
2006 47: 4579-4588. [Abstract] [Full Text] [PDF] Supplementary Table  

Retinal Cell Biology:

Jonathan I. Matsui, Ana L. Egana, Todd R. Sponholtz, Alan R. Adolph, and John E. Dowling

Effects of Ethanol on Photoreceptors and Visual Function in Developing Zebrafish
2006 47: 4589-4597. [Abstract] [Full Text] [PDF]  

Ping Yang, James J. Peairs, Ryotaro Tano, and Glenn J. Jaffe

Oxidant-mediated Akt Activation in Human RPE Cells
2006 47: 4598-4606. [Abstract] [Full Text] [PDF]  

Yoshihiko Usui, Youko Okunuki, Takaaki Hattori, Masaru Takeuchi, Takeshi Kezuka, Hiroshi Goto, and Masahiko Usui

Expression of Costimulatory Molecules on Human Retinoblastoma Cells Y-79: Functional Expression of CD40 and B7H1
2006 47: 4607-4613. [Abstract] [Full Text] [PDF]  

Anne-Lise Glotin, Armelle Calipel, Jean-Yves Brossas, Anne-Marie Faussat, Jacques Tréton, and Frédéric Mascarelli

Sustained versus Transient ERK1/2 Signaling Underlies the Anti- and Proapoptotic Effects of Oxidative Stress in Human RPE Cells
2006 47: 4614-4623. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Raymond O. Beirne, Ruth E. Hogg, Michael R. Stevenson, Margarita B. Zlatkova, Usha Chakravarthy, and Roger S. Anderson

Severity Staging by Early Features of Age-Related Maculopathy Exhibits Weak Relationships with Functional Deficits on SWS Grating Acuity
2006 47: 4624-4631. [Abstract] [Full Text] [PDF]  

Michelle R. Newkirk, Stuart K. Gardiner, Shaban Demirel, and Chris A. Johnson

Assessment of False Positives with the Humphrey Field Analyzer II Perimeter with the SITA Algorithm
2006 47: 4632-4637. [Abstract] [Full Text] [PDF]  

Pauline E. van Eeden, Lisa B. G. Tee, Sherralee Lukehurst, Chooi-May Lai, Elizabeth P. Rakoczy, Lyn D. Beazley, and Sarah A. Dunlop

Early Vascular and Neuronal Changes in a VEGF Transgenic Mouse Model of Retinal Neovascularization
2006 47: 4638-4645. [Abstract] [Full Text] [PDF] Supplementary Movies  

Joanne Wood, Alex Chaparro, Louise Hickson, Nick Thyer, Philippa Carter, Julie Hancock, Adrene Hoe, Ivy Le, Louisa Sahetapy, and Floravel Ybarzabal

The Effect of Auditory and Visual Distracters on the Useful Field of View: Implications for the Driving Task
2006 47: 4646-4650. [Abstract] [Full Text] [PDF]  

Juan Tabernero, Patricia Piers, Antonio Benito, Manuel Redondo, and Pablo Artal

Predicting the Optical Performance of Eyes Implanted with IOLs to Correct Spherical Aberration
2006 47: 4651-4658. [Abstract] [Full Text] [PDF]  

Errata:

Erratum
2006 47: 4198. [Full Text] [PDF]  

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