New Developments:

Jill Hopkins, Alexander Walsh, and Usha Chakravarthy

Fundus Autofluorescence in Age-Related Macular Degeneration: An Epiphenomenon?
2006 47: 2269-2271. [Full Text] [PDF]  

Anatomy and Pathology:

Krish D. Singh, Nicola S. Logan, and Bernard Gilmartin

Three-Dimensional Modeling of the Human Eye Based on Magnetic Resonance Imaging
2006 47: 2272-2279. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Cheryl M. Ethen, Cavan Reilly, Xiao Feng, Timothy W. Olsen, and Deborah A. Ferrington

The Proteome of Central and Peripheral Retina with Progression of Age-Related Macular Degeneration
2006 47: 2280-2290. [Abstract] [Full Text] [PDF]  

Wei Han, Maurice K. H. Yap, Jing Wang, and Shea Ping Yip

Family-Based Association Analysis of Hepatocyte Growth Factor (HGF) Gene Polymorphisms in High Myopia
2006 47: 2291-2299. [Abstract] [Full Text] [PDF] Supplementary Tables  

Ken Kumagai, Yoshinori Nimura, Atsushi Mizota, Nobuyuki Miyahara, Mizuho Aoki, Yoshiya Furusawa, Masaki Takiguchi, Shuichi Yamamoto, and Naohiko Seki

Arpc1b Gene Is a Candidate Prediction Marker for Choroidal Malignant Melanomas Sensitive to Radiotherapy
2006 47: 2300-2304. [Abstract] [Full Text] [PDF]  

Catherine Bowes Rickman, Jessica N. Ebright, Zachary J. Zavodni, Ling Yu, Tianyuan Wang, Stephen P. Daiger, Graeme Wistow, Kathy Boon, and Michael A. Hauser

Defining the Human Macula Transcriptome and Candidate Retinal Disease Genes Using EyeSAGE
2006 47: 2305-2316. [Abstract] [Full Text] [PDF] Supplementary Tables  

Clinical and Epidemiologic Research:

Manoharan Shunmugam and Augusto Azuara-Blanco

The Quality of Reporting of Diagnostic Accuracy Studies in Glaucoma Using the Heidelberg Retina Tomograph
2006 47: 2317-2323. [Abstract] [Full Text] [PDF]  

Praveen K. Nirmalan, Sannapaneni Krishnaiah, Bindiganavale R. Shamanna, Gullapalli N. Rao, and Ravi Thomas

A Population-Based Assessment of Presbyopia in the State of Andhra Pradesh, South India: The Andhra Pradesh Eye Disease Study
2006 47: 2324-2328. [Abstract] [Full Text] [PDF]  

Cécile Delcourt, Isabelle Carrière, Martine Delage, Pascale Barberger-Gateau, Wolfgang Schalch, and the POLA Study Group

Plasma Lutein and Zeaxanthin and Other Carotenoids as Modifiable Risk Factors for Age-Related Maculopathy and Cataract: The POLA Study
2006 47: 2329-2335. [Abstract] [Full Text] [PDF]  

Debra A. Schaumberg, William G. Christen, Piotr Kozlowski, David T. Miller, Paul M. Ridker, and Robert Y. L. Zee

A Prospective Assessment of the Y402H Variant in Complement Factor H, Genetic Variants in C-Reactive Protein, and Risk of Age-Related Macular Degeneration
2006 47: 2336-2340. [Abstract] [Full Text] [PDF]  

Tien Yin Wong, F. M. Amirul Islam, Ronald Klein, Barbara E. K. Klein, Mary Frances Cotch, Cecilia Castro, A. Richey Sharrett, and Eyal Shahar

Retinal Vascular Caliber, Cardiovascular Risk Factors, and Inflammation: The Multi-Ethnic Study of Atherosclerosis (MESA)
2006 47: 2341-2350. [Abstract] [Full Text] [PDF]  

Son C. Huynh, Xiu Ying Wang, Elena Rochtchina, and Paul Mitchell

Distribution of Macular Thickness by Optical Coherence Tomography: Findings from a Population-Based Study of 6-Year-Old Children
2006 47: 2351-2357. [Abstract] [Full Text] [PDF]  

Cornea:

Jeong Goo Lee and EunDuck P. Kay

Cross-talk among Rho GTPases Acting Downstream of PI 3-Kinase Induces Mesenchymal Transformation of Corneal Endothelial Cells Mediated by FGF-2
2006 47: 2358-2368. [Abstract] [Full Text] [PDF]  

Ling C. Huang, Tihomira D. Petkova, Rose Y. Reins, Rita J. Proske, and Alison M. McDermott

Multifunctional Roles of Human Cathelicidin (LL-37) at the Ocular Surface
2006 47: 2369-2380. [Abstract] [Full Text] [PDF]  

Wei Li, Hua He, Ching-Liang Kuo, Yingying Gao, Tetsuya Kawakita, and Scheffer C. G. Tseng

Basement Membrane Dissolution and Reassembly by Limbal Corneal Epithelial Cells Expanded on Amniotic Membrane
2006 47: 2381-2389. [Abstract] [Full Text] [PDF]  

Yuntao Zhang, Ingo Schmack, Daniel G. Dawson, Hans E. Grossniklaus, Abigail H. Conrad, Yutaka Kariya, Kiyoshi Suzuki, Henry F. Edelhauser, and Gary W. Conrad

Keratan Sulfate and Chondroitin/Dermatan Sulfate in Maximally Recovered Hypocellular Stromal Interface Scars of Postmortem Human LASIK Corneas
2006 47: 2390-2396. [Abstract] [Full Text] [PDF]  

Jie Ouyang, Ying-Cheng Shen, Lung-Kun Yeh, Wei Li, Brad M. Coyle, Chia-Yang Liu, and M. Elizabeth Fini

Pax6 Overexpression Suppresses Cell Proliferation and Retards the Cell Cycle in Corneal Epithelial Cells
2006 47: 2397-2407. [Abstract] [Full Text] [PDF] Supplementary Figure  

Kenneth J. Mandell, Glenn P. Holley, Charles A. Parkos, and Henry F. Edelhauser

Antibody Blockade of Junctional Adhesion Molecule-A in Rabbit Corneal Endothelial Tight Junctions Produces Corneal Swelling
2006 47: 2408-2416. [Abstract] [Full Text] [PDF]  

Matthew J. German, Hubert M. Pollock, Bojun Zhao, Mark J. Tobin, Azzedine Hammiche, Adam Bentley, Leanne J. Cooper, Francis L. Martin, and Nigel J. Fullwood

Characterization of Putative Stem Cell Populations in the Cornea Using Synchrotron Infrared Microspectroscopy
2006 47: 2417-2421. [Abstract] [Full Text] [PDF]  

Dan Wu, Tie Li, Zhenyu Lu, Wei Dai, Ming Xu, and Luo Lu

Effect of CTCF-Binding Motif on Regulation of PAX6 Transcription
2006 47: 2422-2429. [Abstract] [Full Text] [PDF]  

Nick Di Girolamo, Denis Wakefield, and Minas T. Coroneo

UVB-Mediated Induction of Cytokines and Growth Factors in Pterygium Epithelial Cells Involves Cell Surface Receptors and Intracellular Signaling
2006 47: 2430-2437. [Abstract] [Full Text] [PDF]  

Lei Liu, Dirk Hartwig, Susanne Harloff, Philip Herminghaus, Thilo Wedel, Karsten Kasper, and Gerd Geerling

Corneal Epitheliotrophic Capacity of Three Different Blood-Derived Preparations
2006 47: 2438-2444. [Abstract] [Full Text] [PDF]  

Srihari Narayanan, William L. Miller, and Alison M. McDermott

Conjunctival Cytokine Expression in Symptomatic Moderate Dry Eye Subjects
2006 47: 2445-2450. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Alessandro Serra, Louis F. Dell’Osso, Jonathan B. Jacobs, and Robert A. Burnstine

Combined Gaze-Angle and Vergence Variation in Infantile Nystagmus: Two Therapies That Improve the High-Visual-Acuity Field and Methods to Measure It
2006 47: 2451-2460. [Abstract] [Full Text] [PDF]  

Brian C. Anderson, Stephen P. Christiansen, Steven Grandt, Robert W. Grange, and Linda K. McLoon

Increased Extraocular Muscle Strength with Direct Injection of Insulin-like Growth Factor-I
2006 47: 2461-2467. [Abstract] [Full Text] [PDF]  

Janice M. Wensveen, Ronald S. Harwerth, Li-Fang Hung, Ramkumar Ramamirtham, Chea-su Kee, and Earl L. Smith, III

Brief Daily Periods of Unrestricted Vision Can Prevent Form-Deprivation Amblyopia
2006 47: 2468-2477. [Abstract] [Full Text] [PDF]  

Elizabeth L. Irving, Martin J. Steinbach, Linda Lillakas, Raiju J. Babu, and Natalie Hutchings

Horizontal Saccade Dynamics across the Human Life Span
2006 47: 2478-2484. [Abstract] [Full Text] [PDF]  

Jun-Pil Jee, Ho-Kyung Choung, Chong-Kook Kim, and Jeong-Min Hwang

Polytetrafluoroethylene/Polylactide-co-Glycolide Laminate Containing Dexamethasone Allows Delayed Adjustable Strabismus Surgery in a Rabbit Model
2006 47: 2485-2490. [Abstract] [Full Text] [PDF]  

Glaucoma:

Hani Levkovitch-Verbin, Rima Dardik, Shelly Vander, Yael Nisgav, Maya Kalev-Landoy, and Shlomo Melamed

Experimental Glaucoma and Optic Nerve Transection Induce Simultaneous Upregulation of Proapoptotic and Prosurvival Genes
2006 47: 2491-2497. [Abstract] [Full Text] [PDF]  

Akihisa Matsubara, Toru Nakazawa, Deeba Husain, Eirini Iliaki, Edward Connolly, Norman A. Michaud, Evangelos S. Gragoudas, and Joan W. Miller

Investigating the Effect of Ciliary Body Photodynamic Therapy in a Glaucoma Mouse Model
2006 47: 2498-2507. [Abstract] [Full Text] [PDF]  

Sanjoy K. Bhattacharya, John S. Crabb, Vera L. Bonilha, Xiaorong Gu, Hidenari Takahara, and John W. Crabb

Proteomics Implicates Peptidyl Arginine Deiminase 2 and Optic Nerve Citrullination in Glaucoma Pathogenesis
2006 47: 2508-2514. [Abstract] [Full Text] [PDF] Supplementary Material  

Ayman A. M. Shouman, Ahmed Helal, Mohamed A. Marzouk, and Eman M. A. Zaki

Methylcellulose, a Healing Inhibitor Factor in an Animal Model of Trabeculectomy
2006 47: 2515-2519. [Abstract] [Full Text] [PDF]  

Felipe A. Medeiros, Pamela A. Sample, Linda M. Zangwill, Jeffrey M. Liebmann, Christopher A. Girkin, and Robert N. Weinreb

A Statistical Approach to the Evaluation of Covariate Effects on the Receiver Operating Characteristic Curves of Diagnostic Tests in Glaucoma
2006 47: 2520-2527. [Abstract] [Full Text] [PDF]  

Emer Henry, David E. Newby, David J. Webb, Patrick W. F. Hadoke, and Colm J. O’Brien

Altered Endothelin-1 Vasoreactivity in Patients with Untreated Normal-Pressure Glaucoma
2006 47: 2528-2532. [Abstract] [Full Text] [PDF]  

Khaled K. Abu-Amero, Jose Morales, and Thomas M. Bosley

Mitochondrial Abnormalities in Patients with Primary Open-Angle Glaucoma
2006 47: 2533-2541. [Abstract] [Full Text] [PDF]  

Michael A. Hauser, R. Rand Allingham, Kevin Linkroum, Jun Wang, Karen LaRocque-Abramson, Dayse Figueiredo, Cecilia Santiago-Turla, Elizabeth A. del Bono, Jonathan L. Haines, Margaret A. Pericak-Vance, and Janey L. Wiggs

Distribution of WDR36 DNA Sequence Variants in Patients with Primary Open-Angle Glaucoma
2006 47: 2542-2546. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Sunao Sugita, Hiroshi Takase, Chikako Taguchi, Yasuhisa Imai, Koju Kamoi, Tatsushi Kawaguchi, Yoshiharu Sugamoto, Yuri Futagami, Kyogo Itoh, and Manabu Mochizuki

Ocular Infiltrating CD4⁺ T Cells from Patients with Vogt-Koyanagi-Harada Disease Recognize Human Melanocyte Antigens
2006 47: 2547-2554. [Abstract] [Full Text] [PDF]  

Grazyna Adamus, Gregory G. Burrows, Arthur A. Vandenbark, and Halina Offner

Treatment of Autoimmune Anterior Uveitis with Recombinant TCR Ligands
2006 47: 2555-2561. [Abstract] [Full Text] [PDF]  

Xue-Hai Jin, Kazuhiro Ohgami, Kenji Shiratori, Yukari Suzuki, Takeshi Hirano, Yoshikazu Koyama, Kazuhiko Yoshida, Iliyana Ilieva, Ken Iseki, and Shigeaki Ohno

Inhibitory Effects of Lutein on Endotoxin-Induced Uveitis in Lewis Rats
2006 47: 2562-2568. [Abstract] [Full Text] [PDF]  

Lens:

Weimin Guo, Fu Shang, Qing Liu, Lyudmila Urim, Minlei Zhang, and Allen Taylor

Ubiquitin–Proteasome Pathway Function Is Required for Lens Cell Proliferation and Differentiation
2006 47: 2569-2575. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Chi Wai Do, Kim Peterson-Yantorno, and Mortimer M. Civan

Swelling-Activated Cl^– Channels Support Cl^– Secretion by Bovine Ciliary Epithelium
2006 47: 2576-2582. [Abstract] [Full Text] [PDF]  

Soile Nymark, Charlotte Haldin, Heikki Tenhu, and Ari Koskelainen

A New Method for Measuring Free Drug Concentration: Retinal Tissue as a Biosensor
2006 47: 2583-2588. [Abstract] [Full Text] [PDF]  

Edward M. Barnett, Boobalan Elangovan, Kristin E. Bullok, and David Piwnica-Worms

Selective Cell Uptake of Modified Tat Peptide–Fluorophore Conjugates in Rat Retina in Ex Vivo and In Vivo Models
2006 47: 2589-2595. [Abstract] [Full Text] [PDF]  

Brian C. Gilger, Jacklyn H. Salmon, David A. Wilkie, Lars P. J. Cruysberg, Jonghyeon Kim, Matt Hayat, Hyuncheol Kim, Stephanie Kim, Peng Yuan, Susan S. Lee, Susan M. Harrington, Patrick R. Murray, Henry F. Edelhauser, Karl G. Csaky, and Michael R. Robinson

A Novel Bioerodible Deep Scleral Lamellar Cyclosporine Implant for Uveitis
2006 47: 2596-2605. [Abstract] [Full Text] [PDF]  

Retina:

Eyal Margalit and Wallace B. Thoreson

Inner Retinal Mechanisms Engaged by Retinal Electrical Stimulation
2006 47: 2606-2612. [Abstract] [Full Text] [PDF]  

Andrew D. Gosbell, Nada Stefanovic, Lyndee L. Scurr, Josefa Pete, Ismail Kola, Ian Favilla, and Judy B. de Haan

Retinal Light Damage: Structural and Functional Effects of the Antioxidant Glutathione Peroxidase-1
2006 47: 2613-2622. [Abstract] [Full Text] [PDF]  

Hadi J. Zambarakji, Toru Nakazawa, Edward Connolly, Anne Marie Lane, Sreedevi Mallemadugula, Michael Kaplan, Norman Michaud, Ali Hafezi-Moghadam, Evangelos S. Gragoudas, and Joan W. Miller

Dose-Dependent Effect of Pitavastatin on VEGF and Angiogenesis in a Mouse Model of Choroidal Neovascularization
2006 47: 2623-2631. [Abstract] [Full Text] [PDF]  

Barbara Zangerl, Qi Sun, Jarek Pillardy, Jennifer L. Johnson, Peter A. Schweitzer, Alvaro G. Hernandez, Lei Liu, Gregory M. Acland, and Gustavo D. Aguirre

Development and Characterization of a Normalized Canine Retinal cDNA Library for Genomic and Expression Studies
2006 47: 2632-2638. [Abstract] [Full Text] [PDF]  

Kegao Liu, James D. Akula, Christopher Falk, Ronald M. Hansen, and Anne B. Fulton

The Retinal Vasculature and Function of the Neural Retina in a Rat Model of Retinopathy of Prematurity
2006 47: 2639-2647. [Abstract] [Full Text] [PDF]  

Steffen Schmitz-Valckenberg, Almut Bindewald-Wittich, Joanna Dolar-Szczasny, Jens Dreyhaupt, Sebastian Wolf, Hendrik P. N. Scholl, Frank G. Holz for the Fundus Autofluorescence in Age-Related Macular Degeneration Study Group

Correlation between the Area of Increased Autofluorescence Surrounding Geographic Atrophy and Disease Progression in Patients with AMD
2006 47: 2648-2654. [Abstract] [Full Text] [PDF]  

John Chopin Hwang, Jackie W. K. Chan, Stanley Chang, and R. Theodore Smith

Predictive Value of Fundus Autofluorescence for Development of Geographic Atrophy in Age-Related Macular Degeneration
2006 47: 2655-2661. [Abstract] [Full Text] [PDF]  

Anthony S. L. Kwan, Sarojini Vijayasekaran, Ian L. McAllister, Paula K. Yu, and Dao-Yi Yu

A Study of Retinal Penetration of Intravitreal Tenecteplase in Pigs
2006 47: 2662-2667. [Abstract] [Full Text] [PDF]  

Bruce A. Berkowitz, Robin Roberts, Dennis J. Goebel, and Hongmei Luan

Noninvasive and Simultaneous Imaging of Layer-Specific Retinal Functional Adaptation by Manganese-Enhanced MRI
2006 47: 2668-2674. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Yong-Ha Youn, Jeehee Hong, and Janice M. Burke

Cell Phenotype in Normal Epithelial Cell Lines with High Endogenous N-Cadherin: Comparison of RPE to an MDCK Subclone
2006 47: 2675-2685. [Abstract] [Full Text] [PDF]  

Shingo Satofuka, Atsuhiro Ichihara, Norihiro Nagai, Kenji Yamashiro, Takashi Koto, Hajime Shinoda, Kousuke Noda, Yoko Ozawa, Makoto Inoue, Kazuo Tsubota, Fumiaki Suzuki, Yuichi Oike, and Susumu Ishida

Suppression of Ocular Inflammation in Endotoxin-Induced Uveitis by Inhibiting Nonproteolytic Activation of Prorenin
2006 47: 2686-2692. [Abstract] [Full Text] [PDF]  

James J. Tomasek, Carol J. Haaksma, Robert J. Schwartz, Duc T. Vuong, Sarah X. Zhang, John D. Ash, Jian-xing Ma, and Muayyad R. Al-Ubaidi

Deletion of Smooth Muscle -Actin Alters Blood–Retina Barrier Permeability and Retinal Function
2006 47: 2693-2700. [Abstract] [Full Text] [PDF]  

Allen C. Clermont, Mark Cahill, Haytham Salti, Susan L. Rook, Christian Rask-Madsen, Lucy Goddard, Jun S. Wong, Dahlia Bursell, Sven E. Bursell, and Lloyd Paul Aiello

Hepatocyte Growth Factor Induces Retinal Vascular Permeability via MAP-Kinase and PI-3 Kinase without Altering Retinal Hemodynamics
2006 47: 2701-2708. [Abstract] [Full Text] [PDF]  

Khoi-Nguyen Ha, Yan Chen, Jiyang Cai, and Paul Sternberg, Jr

Increased Glutathione Synthesis through an ARE-Nrf2–Dependent Pathway by Zinc in the RPE: Implication for Protection against Oxidative Stress
2006 47: 2709-2715. [Abstract] [Full Text] [PDF]  

Andrée Rothermel, Katja Volpert, Mirjam Burghardt, Christina Lantzsch, Andrea A. Robitzki, and Paul G. Layer

Knock-Down of GFR4 Expression by RNA Interference Affects the Development of Retinal Cell Types in Three-Dimensional Histiotypic Retinal Spheres
2006 47: 2716-2725. [Abstract] [Full Text] [PDF]  

Roselie M. H. Diederen, Catherine A. Starnes, Bruce A. Berkowitz, and Barry S. Winkler

Reexamining the Hyperglycemic Pseudohypoxia Hypothesis of Diabetic Oculopathy
2006 47: 2726-2731. [Abstract] [Full Text] [PDF]  

Visual Neurophysiology:

Bo Lei, Gang Yao, Keqing Zhang, Kurt J. Hofeldt, and Bo Chang

Study of Rod- and Cone-Driven Oscillatory Potentials in Mice
2006 47: 2732-2738. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Sharon A. Haymes, Kenneth F. Roberts, Alan F. Cruess, Marcelo T. Nicolela, Raymond P. LeBlanc, Michael S. Ramsey, Balwantray C. Chauhan, and Paul H. Artes

The Letter Contrast Sensitivity Test: Clinical Evaluation of a New Design
2006 47: 2739-2745. [Abstract] [Full Text] [PDF]  

Erratum:

Erratum
2006 47: 2279. [Full Text] [PDF]  

Erratum
2006 47: 2279. [Full Text] [PDF]  

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