Lectures:

David S. Papermaster

Introducing Nicolas G. Bazan, the 2007 Recipient of the Proctor Medal
2007 48: 4864-4865. [Full Text] [PDF]  

Nicolas G. Bazan

Homeostatic Regulation of Photoreceptor Cell Integrity: Significance of the Potent Mediator Neuroprotectin D1 Biosynthesized from Docosahexaenoic Acid The Proctor Lecture
2007 48: 4866-4881. [Full Text] [PDF]  

New Developments:

Igor Kozak, Lingyun Cheng, Gabriel A. Silva, and William R. Freeman

Testing of Intraocular Drugs for Clinical Use
2007 48: 4861-4863. [Full Text] [PDF]  

Anatomy and Pathology:

Irene Notting, Jeroen Buijs, Ratna Mintardjo, Geertje van der Horst, Slobodan Vukicevic, Clemens Lowik, Nicoline Schalij-Delfos, Jan Keunen, and Gabri van der Pluijm

Bone Morphogenetic Protein 7 Inhibits Tumor Growth of Human Uveal Melanoma In Vivo
2007 48: 4882-4889. [Abstract] [Full Text] [PDF]  

Tal Meir, Rinat Dror, Xueping Yu, Jiang Qian, Itamar Simon, Jacob Pe’er, and Itay Chowers

Molecular Characteristics of Liver Metastases from Uveal Melanoma
2007 48: 4890-4896. [Abstract] [Full Text] [PDF] Supplementary Material  

Fiona Henriquez, Christoph Janssen, Ewan G. Kemp, and Fiona Roberts

The T1799A BRAF Mutation Is Present in Iris Melanoma
2007 48: 4897-4900. [Abstract] [Full Text] [PDF]  

Biochemistry and Molecular Biology:

Jagadeesan Madhavan, Karunakaran Coral, Kandalam Mallikarjuna, Timothy W. Corson, Nagpal Amit, Vikas Khetan, Ronnie George, Jyotirmay Biswas, Brenda L. Gallie, and Govindasamy Kumaramanickavel

High Expression of KIF14 in Retinoblastoma: Association with Older Age at Diagnosis
2007 48: 4901-4906. [Abstract] [Full Text] [PDF]  

Danian Gu, William A. Beltran, Zexiao Li, Gregory M. Acland, and Gustavo D. Aguirre

Clinical Light Exposure, Photoreceptor Degeneration, and AP-1 Activation: A Cell Death or Cell Survival Signal in the Rhodopsin Mutant Retina?
2007 48: 4907-4918. [Abstract] [Full Text] [PDF]  

Walter van Gils, Hanneke W. Mensink, Emine Kilic, Jolanda Vaarwater, Michael M. Verbiest, Dion Paridaens, Gregorius P. Luyten, Annelies de Klein, and Hennie T. Brüggenwirth

Expression of APITD1 Is Not Related to Copy Number Changes of Chromosomal Region 1p36 or the Prognosis of Uveal Melanoma
2007 48: 4919-4923. [Abstract] [Full Text] [PDF]  

Maria Schäche, Andrea J. Richardson, Kelly K. Pertile, Mohamed Dirani, Katrina Scurrah, and Paul N. Baird

Genetic Mapping of Myopia Susceptibility Loci
2007 48: 4924-4929. [Abstract] [Full Text] [PDF]  

Arun K. Bajpai, Eva Blaskova, Suresh B. Pakala, Tieqiang Zhao, Wayne C. Glasgow, John S. Penn, Dianna A. Johnson, and Gadiparthi N. Rao

15(S)-HETE Production in Human Retinal Microvascular Endothelial Cells by Hypoxia: Novel Role for MEK1 in 15(S)-HETE–Induced Angiogenesis
2007 48: 4930-4938. [Abstract] [Full Text] [PDF]  

Clinical and Epidemiologic Research:

Louis Tong, Yiong-Huak Chan, Gus Gazzard, Seng-Chee Loon, Allan Fong, Prabakaran Selvaraj, Paul R. Healey, Donald Tan, Tien Yin Wong, and Seang Mei Saw

Heidelberg Retinal Tomography of Optic Disc and Nerve Fiber Layer in Singapore Children: Variations with Disc Tilt and Refractive Error
2007 48: 4939-4944. [Abstract] [Full Text] [PDF]  

Ning Cheung, Louis Tong, Gabriella Tikellis, Seang Mei Saw, Paul Mitchell, Jie Jin Wang, and Tien Yin Wong

Relationship of Retinal Vascular Caliber with Optic Disc Diameter in Children
2007 48: 4945-4948. [Abstract] [Full Text] [PDF]  

Paul Esteso, Aaron Castanon, Silvia Toledo, Marco A. Pereyra Rito, Anne Ervin, Robert Wojciechowski, and Nathan G. Congdon

Correction of Moderate Myopia Is Associated with Improvement in Self-Reported Visual Functioning among Mexican School-Aged Children
2007 48: 4949-4954. [Abstract] [Full Text] [PDF]  

Robert W. Massof, James T. Deremeik, William L. Park, and Lori L. Grover

Self-Reported Importance and Difficulty of Driving in a Low-Vision Clinic Population
2007 48: 4955-4962. [Abstract] [Full Text] [PDF]  

Gianni Virgili, Francesca Menchini, Andrea F. Dimastrogiovanni, Emilio Rapizzi, Ugo Menchini, Francesco Bandello, and Raffaella Gortana Chiodini

Optical Coherence Tomography versus Stereoscopic Fundus Photography or Biomicroscopy for Diagnosing Diabetic Macular Edema: A Systematic Review
2007 48: 4963-4973. [Abstract] [Full Text] [PDF]  

Kenji Sakata, Lisandro M. Sakata, Viviane M. Sakata, Cintia Santini, Luisa M. Hopker, Ricardo Bernardes, Cristina Yabumoto, and Ana T. R. Moreira

Prevalence of Glaucoma in a South Brazilian Population: Projeto Glaucoma
2007 48: 4974-4979. [Abstract] [Full Text] [PDF]  

Cornea:

Margot L. Goodkin, Seth Epstein, Penny A. Asbell, and John A. Blaho

Nuclear Translocation of NF-B Precedes Apoptotic Poly(ADP-ribose) Polymerase Cleavage during Productive HSV-1 Replication in Corneal Epithelial Cells
2007 48: 4980-4988. [Abstract] [Full Text] [PDF]  

Andrea Kabosova, Dimitri T. Azar, Gregory A. Bannikov, Kevin P. Campbell, Madeleine Durbeej, Reza F. Ghohestani, Jonathan C. R. Jones, M. Cristina Kenney, Manuel Koch, Yoshifumi Ninomiya, Bruce L. Patton, Mats Paulsson, Yoshikazu Sado, E. Helene Sage, Takako Sasaki, Lydia M. Sorokin, Marie-France Steiner-Champliaud, Tung-Tien Sun, Nirmala SundarRaj, Rupert Timpl, Ismo Virtanen, and Alexander V. Ljubimov

Compositional Differences between Infant and Adult Human Corneal Basement Membranes
2007 48: 4989-4999. [Abstract] [Full Text] [PDF]  

Toihiri Said, Mélody Dutot, Raymond Christon, Jean-Louis Beaudeux, Chantal Martin, Jean-Michel Warnet, and Patrice Rat

Benefits and Side Effects of Different Vegetable Oil Vectors on Apoptosis, Oxidative Stress, and P2X7 Cell Death Receptor Activation
2007 48: 5000-5006. [Abstract] [Full Text] [PDF]  

Jayne S. Weiss, Howard S. Kruth, Helena Kuivaniemi, Gerard Tromp, Peter S. White, R. Scott Winters, Walter Lisch, Wolfram Henn, Elke Denninger, Matthias Krause, Paul Wasson, Neil Ebenezer, Sunil Mahurkar, and Michael L. Nickerson

Mutations in the UBIAD1 Gene on Chromosome Short Arm 1, Region 36, Cause Schnyder Crystalline Corneal Dystrophy
2007 48: 5007-5012. [Abstract] [Full Text] [PDF]  

Ai Kitano, Shizuya Saika, Osamu Yamanaka, Kazuo Ikeda, Yuka Okada, Kumi Shirai, and Peter S. Reinach

Emodin Suppression of Ocular Surface Inflammatory Reaction
2007 48: 5013-5022. [Abstract] [Full Text] [PDF]  

Matei S. Petrescu, Chonna L. Larry, Robert A. Bowden, George W. Williams, Debjani Gagen, Zhijie Li, C. Wayne Smith, and Alan R. Burns

Neutrophil Interactions with Keratocytes during Corneal Epithelial Wound Healing: A Role for CD18 Integrins
2007 48: 5023-5029. [Abstract] [Full Text] [PDF]  

Dimitris Karamichos, Neema Lakshman, and W. Matthew Petroll

Regulation of Corneal Fibroblast Morphology and Collagen Reorganization by Extracellular Matrix Mechanical Properties
2007 48: 5030-5037. [Abstract] [Full Text] [PDF] Movies  

Yiqin Du, Nirmala SundarRaj, Martha L. Funderburgh, Stephen A. Harvey, David E. Birk, and James L. Funderburgh

Secretion and Organization of a Cornea-like Tissue In Vitro by Stem Cells from Human Corneal Stroma
2007 48: 5038-5045. [Abstract] [Full Text] [PDF]  

Eye Movements, Strabismus, Amblyopia, and Neuro-Ophthalmology:

Roger W. Li, Allison Provost, and Dennis M. Levi

Extended Perceptual Learning Results in Substantial Recovery of Positional Acuity and Visual Acuity in Juvenile Amblyopia
2007 48: 5046-5051. [Abstract] [Full Text] [PDF]  

Glaucoma:

David S. Friedman, Harry A. Quigley, Laurie Gelb, Jason Tan, Jay Margolis, Sonali N. Shah, Elizabeth E. Kim, Thom Zimmerman, and Steven R. Hahn

Using Pharmacy Claims Data to Study Adherence to Glaucoma Medications: Methodology and Findings of the Glaucoma Adherence and Persistency Study (GAPS)
2007 48: 5052-5057. [Abstract] [Full Text] [PDF] Appendices  

Gulab S. Zode, Abbot F. Clark, and Robert J. Wordinger

Activation of the BMP Canonical Signaling Pathway in Human Optic Nerve Head Tissue and Isolated Optic Nerve Head Astrocytes and Lamina Cribrosa Cells
2007 48: 5058-5067. [Abstract] [Full Text] [PDF]  

Hongli Yang, J. Crawford Downs, Anthony Bellezza, Hilary Thompson, and Claude F. Burgoyne

3-D Histomorphometry of the Normal and Early Glaucomatous Monkey Optic Nerve Head: Prelaminar Neural Tissues and Cupping
2007 48: 5068-5084. [Abstract] [Full Text] [PDF] Supplementary Figures  

David Goldblum, Anna Kipfer-Kauer, Gian-Marco Sarra, Sebastian Wolf, and Beatrice E. Frueh

Distribution of Amyloid Precursor Protein and Amyloid-ß Immunoreactivity in DBA/2J Glaucomatous Mouse Retinas
2007 48: 5085-5090. [Abstract] [Full Text] [PDF]  

Immunology and Microbiology:

Purushottam Jha, Bharati Matta, Valeriy Lyzogubov, Ruslana Tytarenko, Puran S. Bora, and Nalini S. Bora

Crucial Role of Apoptosis in the Resolution of Experimental Autoimmune Anterior Uveitis
2007 48: 5091-5100. [Abstract] [Full Text] [PDF]  

Huan Yang, Bo Wu, Erdem Tüzün, Shamsher S. Saini, Jing Li, Windy Allman, Stephen Higgs, Tian Lin Xiao, and Premkumar Christadoss

A New Mouse Model of Autoimmune Ocular Myasthenia Gravis
2007 48: 5101-5111. [Abstract] [Full Text] [PDF]  

Tat Fong Ng, Nobuyoshi Kitaichi, and Andrew W. Taylor

In Vitro–Generated Autoimmune Regulatory T Cells Enhance Intravitreous Allogeneic Retinal Graft Survival
2007 48: 5112-5117. [Abstract] [Full Text] [PDF]  

Curtis R. Brandt, Radeekorn Akkarawongsa, Sharon Altmann, Gilbert Jose, Aaron W. Kolb, Alan J. Waring, and Robert I. Lehrer

Evaluation of a -Defensin in a Murine Model of Herpes Simplex Virus Type 1 Keratitis
2007 48: 5118-5124. [Abstract] [Full Text] [PDF]  

Richard J. O’Callaghan, Clare C. McCormick, Armando R. Caballero, Mary E. Marquart, Hattie P. Gatlin, and Jonathan D. Fratkin

Age-Related Differences in Rabbits during Experimental Staphylococcus aureus Keratitis
2007 48: 5125-5131. [Abstract] [Full Text] [PDF]  

Lens:

Joshua T. Pittenger, John F. Hess, and Paul G. FitzGerald

Identifying the Role of Specific Motifs in the Lens Fiber Cell–Specific Intermediate Filament Phakosin
2007 48: 5132-5141. [Abstract] [Full Text] [PDF]  

Julie Lim, Ling Li, Marc D. Jacobs, Joerg Kistler, and Paul J. Donaldson

Mapping of Glutathione and Its Precursor Amino Acids Reveals a Role for GLYT2 in Glycine Uptake in the Lens Core
2007 48: 5142-5151. [Abstract] [Full Text] [PDF]  

Physiology and Pharmacology:

Jyotirmoy Kusari, Sheila Zhou, Edwin Padillo, Kenneth G. Clarke, and Daniel W. Gil

Effect of Memantine on Neuroretinal Function and Retinal Vascular Changes of Streptozotocin-Induced Diabetic Rats
2007 48: 5152-5159. [Abstract] [Full Text] [PDF]  

Retina:

Asimina Mataftsi, Daniel F. Schorderet, Louisa Chachoua, Myriam Boussalah, Mohamed T. Nouri, Daniel Barthelmes, François-Xavier Borruat, and Francis L. Munier

Novel TULP1 Mutation Causing Leber Congenital Amaurosis or Early Onset Retinal Degeneration
2007 48: 5160-5167. [Abstract] [Full Text] [PDF]  

Ana J. Chucair, Nora P. Rotstein, John Paul SanGiovanni, Alexandrine During, Emily Y. Chew, and Luis E. Politi

Lutein and Zeaxanthin Protect Photoreceptors from Apoptosis Induced by Oxidative Stress: Relation with Docosahexaenoic Acid
2007 48: 5168-5177. [Abstract] [Full Text] [PDF]  

Sinisa D. Grozdanic, Milan Matic, Donald S. Sakaguchi, and Randy H. Kardon

Evaluation of Retinal Status Using Chromatic Pupil Light Reflex Activity in Healthy and Diseased Canine Eyes
2007 48: 5178-5183. [Abstract] [Full Text] [PDF]  

Yingli Fu, M. Lourdes Ponce, Michelle Thill, Peng Yuan, Nam Sun Wang, and Karl G. Csaky

Angiogenesis Inhibition and Choroidal Neovascularization Suppression by Sustained Delivery of an Integrin Antagonist, EMD478761
2007 48: 5184-5190. [Abstract] [Full Text] [PDF]  

Li-ping Yang, Le-meng Wu, Xiu-juan Guo, and Mark O. M. Tso

Activation of Endoplasmic Reticulum Stress in Degenerating Photoreceptors of the rd1 Mouse
2007 48: 5191-5198. [Abstract] [Full Text] [PDF]  

Mariacarmela Allocca, Umberto Di Vicino, Marco Petrillo, Francesca Carlomagno, Luciano Domenici, and Alberto Auricchio

Constitutive and AP20187-Induced Ret Activation in Photoreceptors Does Not Protect from Light-Induced Damage
2007 48: 5199-5206. [Abstract] [Full Text] [PDF]  

Monika Ecsedy, Anna Szamosi, Cecilia Karkó, Laszlo Zubovics, Balazs Varsányi, Janos Németh, and Zsuzsa Récsán

A Comparison of Macular Structure Imaged by Optical Coherence Tomography in Preterm and Full-Term Children
2007 48: 5207-5211. [Abstract] [Full Text] [PDF]  

Timothy Y. Y. Lai, Tsz Kin Ng, Pancy O. S. Tam, Gary H. F. Yam, Jasmine W. S. Ngai, Wai-Man Chan, David T. L. Liu, Dennis S. C. Lam, and Chi Pui Pang

Genotype–Phenotype Analysis of Bietti’s Crystalline Dystrophy in Patients with CYP4V2 Mutations
2007 48: 5212-5220. [Abstract] [Full Text] [PDF]  

Claire M. Gelfman, Peter Vogel, Tawfik M. Issa, C. Alexander Turner, Wang-Sik Lee, Stuart Kornfeld, and Dennis S. Rice

Mice Lacking /ß Subunits of GlcNAc-1-Phosphotransferase Exhibit Growth Retardation, Retinal Degeneration, and Secretory Cell Lesions
2007 48: 5221-5228. [Abstract] [Full Text] [PDF]  

Caroline B. Lupien, Carl Bolduc, Solange Landreville, and Christian Salesse

Comparison between the Gene Expression Profile of Human Müller Cells and Two Spontaneous Müller Cell Lines
2007 48: 5229-5242. [Abstract] [Full Text] [PDF] Supplementary Tables  

Guifang Zhang, Xiao Feng, Kathy Wabner, Chris Fandrey, Amir Naqwi, Timothy Wiedmann, and Timothy W. Olsen

Intraocular Nanoparticle Drug Delivery: A Pilot Study Using an Aerosol during Pars Plana Vitrectomy
2007 48: 5243-5249. [Abstract] [Full Text] [PDF]  

Kevin W. Bronson-Castain, Marcus A. Bearse, Jr, Ying Han, Marilyn E. Schneck, Shirin Barez, and Anthony J. Adams

Association between Multifocal ERG Implicit Time Delays and Adaptation in Patients with Diabetes
2007 48: 5250-5256. [Abstract] [Full Text] [PDF]  

Retinal Cell Biology:

Ermelindo C. Leal, Ayyakkannu Manivannan, Ken-Ichi Hosoya, Tetsuya Terasaki, José Cunha-Vaz, António Francisco Ambrósio, and John V. Forrester

Inducible Nitric Oxide Synthase Isoform Is a Key Mediator of Leukostasis and Blood-Retinal Barrier Breakdown in Diabetic Retinopathy
2007 48: 5257-5265. [Abstract] [Full Text] [PDF]  

Philip E. B. Nickerson, Jason G. Emsley, Tanya Myers, and David B. Clarke

Proliferation and Expression of Progenitor and Mature Retinal Phenotypes in the Adult Mammalian Ciliary Body after Retinal Ganglion Cell Injury
2007 48: 5266-5275. [Abstract] [Full Text] [PDF]  

Robert J. Walker and Jena J. Steinle

Role of ß-Adrenergic Receptors in Inflammatory Marker Expression in Müller Cells
2007 48: 5276-5281. [Abstract] [Full Text] [PDF]  

Bärbel Rohrer, Yao Guo, Kannan Kunchithapautham, and Gary S. Gilkeson

Eliminating Complement Factor D Reduces Photoreceptor Susceptibility to Light-Induced Damage
2007 48: 5282-5289. [Abstract] [Full Text] [PDF] Supplementary Table  

Jian-Jang You, Chang-Hao Yang, Jen-Shang Huang, Muh-Shy Chen, and Chung-May Yang

Fractalkine, a CX3C Chemokine, as a Mediator of Ocular Angiogenesis
2007 48: 5290-5298. [Abstract] [Full Text] [PDF]  

Nagavedi S. Umapathy, Jaya P. Gnana-Prakasam, Pamela M. Martin, Barbara Mysona, Ying Dun, Sylvia B. Smith, Vadivel Ganapathy, and Puttur D. Prasad

Cloning and Functional Characterization of the Proton-Coupled Electrogenic Folate Transporter and Analysis of Its Expression in Retinal Cell Types
2007 48: 5299-5305. [Abstract] [Full Text] [PDF]  

Katja N. Volpert, Andrée Rothermel, and Paul G. Layer

GDNF Stimulates Rod Photoreceptors and Dopaminergic Amacrine Cells in Chicken Retinal Reaggregates
2007 48: 5306-5314. [Abstract] [Full Text] [PDF]  

Keisuke Mori, Peter L. Gehlbach, Sho Kabasawa, Izumi Kawasaki, Masataka Oosaki, Hiroyuki Iizuka, Shigehiro Katayama, Takuya Awata, and Shin Yoneya

Coding and Noncoding Variants in the CFH Gene and Cigarette Smoking Influence the Risk of Age-Related Macular Degeneration in a Japanese Population
2007 48: 5315-5319. [Abstract] [Full Text] [PDF]  

Visual Psychophysics and Physiological Optics:

Maria Letizia Salvetat, Marco Zeppieri, Lucia Parisi, and Paolo Brusini

Rarebit Perimetry in Normal Subjects: Test–Retest Variability, Learning Effect, Normative Range, Influence of Optical Defocus, and Cataract Extraction
2007 48: 5320-5331. [Abstract] [Full Text] [PDF]  

Daniel H. Baker, Tim S. Meese, Behzad Mansouri, and Robert F. Hess

Binocular Summation of Contrast Remains Intact in Strabismic Amblyopia
2007 48: 5332-5338. [Abstract] [Full Text] [PDF]  

Erratum:

ERRATUM
2007 48: 4900. [Full Text] [PDF]  

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